Results 21 to 30 of about 4,001,428 (243)

Clinicopathological profile and management of 161 cases of actinic cheilitis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
BACKGROUND:Actinic cheilitis (AC) is a potentially malignant disorder of the lip caused by chronic exposure to ultraviolet radiation from the sun.OBJECTIVES:To evaluate the clinical, demographic, morphological and therapeutic management in AC cases data ...
Maria Luiza Diniz de Sousa Lopes   +4 more
doaj   +2 more sources

C9orf72-Related Neurodegenerative Diseases: From Clinical Diagnosis to Therapeutic Strategies

open access: yesFrontiers in Aging Neuroscience, 2022
Hexanucleotide expansion in C9orf72 has been related to several phenotypes to date, complicating the clinical recognition of these neurodegenerative disorders.
Stefania Zampatti   +7 more
doaj   +1 more source

COVID-19-Current Therapeutical Approaches and Future Perspectives

open access: yes, 2022
The ongoing pandemic of coronavirus disease (COVID-19) stimulated an unprecedented international collaborative effort for rapid diagnosis, epidemiologic surveillance, clinical management, prevention, and treatment.
Camelia Sultana   +6 more
core   +1 more source

Establishing a model of precision-cut liver slices to test for therapeutical approaches of liver disease and regeneration

open access: yes, 2022
Considering the human anatomy, the liver is one of the main metabolic organs and is essential for the appropriate functioning of the immune system.
Hackl, Verena
core   +3 more sources

Marine-Inspired Drugs and Biomaterials in the Perspective of Pancreatic Cancer Therapies

open access: yesMarine Drugs, 2022
Despite its low prevalence, pancreatic cancer (PC) is one of the deadliest, typically characterised as silent in early stages and with a dramatically poor prognosis when in its advanced stages, commonly associated with a high degree of metastasis.
Andreia S. Fernandes   +4 more
doaj   +1 more source

El Continuun causal del envejecimiento: la detección precoz de la demencia y el papel de los factores protectores y de riesgo

open access: yesActa Neurológica Colombiana, 2023
The prevalence of cognitive disorders and dementia increases with age and represents a high cost to society and health services. Some authors have suggested an ongoing process that leads from the cognitive impairments to dementia, with a presentation ...
Carolina Restrepo   +2 more
doaj   +2 more sources

Updates on Diagnostic and Therapeutic Management of Gastrointestinal and Pancreatic NET

open access: yes, 2022
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) comprise a plethora of distinct molecular-pathological, clinical, diagnostical and therapeutical approaches to enable individualized treatment [...
Sebastian Krug   +5 more
core   +1 more source

Approaches to the third ventricle

open access: yesBrazilian Neurosurgery, 2012
The authors review the main technical approaches to the third ventricle, the most common surgical indications and their results. The traditional open techniques are characterized by low rate of residual lesion and risk, although low, epilepsy ...
Ricardo Brandão Fonseca   +2 more
doaj   +1 more source

Vertigem posicional paroxística benigna sem nistagmo: diagnóstico e tratamento Benign paroxysmal positional vertigo without nystagmus: diagnosis and treatment

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
O aparecimento do nistagmo nos testes para diagnosticar a VPPB ainda é considerado importante na caracterização clínica da VPPB. Contudo, na prática cotidiana, existem casos de vertigem gerada pelos movimentos cefálicos, que não se acompanham deste sinal
Gabriella Assumpção Alvarenga   +2 more
doaj   +1 more source

Targeted Therapy with Sirolimus and Nivolumab in a Child with Refractory Multifocal Anaplastic Ependymoma

open access: yesReports, 2021
Pediatric ependymoma (EPN) is the third most common central nervous system (CNS) tumor, with 90% arising intracranially. Management typically involves maximal surgical resection and radiotherapy, but patients’ outcome is poor.
Katia Perruccio   +9 more
doaj   +1 more source

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