Results 231 to 240 of about 28,229 (283)

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Editorial: Clinical guidelines in bipolar disorder: applications and evaluation. [PDF]

Front Psychiatry
Grunze H.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Citicoline and Coenzyme Q10: Therapeutic Agents for Glial Activation Reduction in Ocular Hypertension. [PDF]

Pharmaceuticals (Basel)
Matamoros JA, Rubio-Casado S, Fernández-Albarral JA, Martínez-López MA, Ramírez AI, Salobrar-García E, Marco EM, Paleo-García V, de Hoz R, López-Cuenca I, Elvira-Hurtado L, Sánchez-Puebla L, Ramírez JM, López-Gallardo M, Salazar JJ.   +14 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

In Vivo Functional and Structural Retinal Preservation by Combined Administration of Citicoline and Coenzyme Q10 in a Murine Model of Ocular Hypertension. [PDF]

Int J Mol Sci
Matamoros JA, Salobrar-García E, Salazar JJ, López-Cuenca I, Elvira-Hurtado L, Martínez MA, Rubio-Casado S, Paleo-García V, Hoz R, Ramírez JM, de la Villa P, Fernández-Albarral JA, Ramirez AI.   +12 more
europepmc   +1 more source

Exploring the singularity of human neurons: keep calm and carry on. [PDF]

Front Synaptic Neurosci
Libé-Philippot B.
europepmc   +1 more source

Pelotherapy, thalassotherapy, and electrotherapy for skin treatment: current insights and future perspectives on electropelotherapy. [PDF]

Int J Biometeorol
Almeida L, Rocha F, Candeias C.
europepmc   +1 more source