Results 61 to 70 of about 28,229 (283)
MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
wiley +1 more source
Toxin-Based Therapeutic Approaches [PDF]
Protein toxins confer a defense against predation/grazing or a superior pathogenic competence upon the producing organism. Such toxins have been perfected through evolution in poisonous animals/plants and pathogenic bacteria. Over the past five decades, a lot of effort has been invested in studying their mechanism of action, the way they contribute to ...
Itai Benhar, Assaf Shapira
openaire +3 more sources
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
Los métodos terapéuticos en la psoriasis han variado según localización de las lesiones, gravedad, duración de los brotes, tratamientos previos y edad de los pacientes, pero en realidad no se ha podido afirmar que ningún régimen sea curativo, lo que ...
Omar García López
doaj
Alzheimer’s disease therapies: Selected advances and future perspectives
Among the neurodegenerative diseases, Alzheimer’s disease (AD) represents one of the biggest challenges that the modern health care system has to deal with.
Abdelaziz Ghanemi
doaj +1 more source
The Politics of Vodou: Aids, Access to Health Care and the Use of Culture in Haiti [PDF]
During the past few years, the AIDS campaign in Haiti has been targeting Vodou officiants and organizations. These awareness and training programmes in- form officiants about the transmission and prevention of AIDS, tests for HIV and anti- retroviral ...
Benoît, Catherine
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
After Cesarean vesicouterine fistula (Youssef Syndrome) with successful conservative management
Vesicouterine fistula without vaginal leakage of urine, cyclic hematuria and amenorrhea is a rare condition, identified as Youssef’s syndrome. The most common cause of this syndrome is trauma during a cesarean section.
Julián Oñate Celdrán +1 more
doaj +1 more source
PHARMACOGENETICS APPROACH TO THERAPEUTICS [PDF]
1. Pharmacogenetics refers to the study of genetically controlled variations in drug response. Functional variants caused by single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolising enzymes, transporters, ion channels and drug receptors have been known to be associated with interindividual and interethnic variation in drug response ...
Seok Hwee, Koo, Edmund Jon Deoon, Lee
openaire +2 more sources

