Results 171 to 180 of about 1,302,607 (412)

New method for the study of psychotropic drug effects under simulated clinical conditions [PDF]

arXiv, 2007
The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by repeated agonistic interactions in male mice and investigating the therapeutic and preventive properties of any drug as
arxiv  

Water Extracts of Moringa oleifera Leaves Alter Oxidative Stress–Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells

The Scientific World Journal
Moringa oleifera (MO) has been an important plant for food and traditional medicine in Asian countries, including Indonesia. The leaves of these plants are reported to be rich in antioxidants, vitamins, and micronutrients and have been proven to have ...
Agian Jeffilano Barinda, Wawaimuli Arozal, Harri Hardi, Yulia Ratna Dewi, Muhamad Sadam Safutra, Hee Jae Lee   +5 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

A Text-Book of Therapeutics Including the Essentials of Pharmacology and Materia Medica. [PDF]

, 1928

openalex   +1 more source

Comorbid anxiety predicts lower odds of depression improvement during smartphone-delivered psychotherapy [PDF]

arXiv
Comorbid anxiety disorders are common among patients with major depressive disorder (MDD), and numerous studies have identified an association between comorbid anxiety and resistance to pharmacological depression treatment. However, the impact of anxiety on the effectiveness of non-pharmacological interventions for MDD is not as well understood.
arxiv  

Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study

Journal of Pharmaceutical Health Care and Sciences
Background Post-stroke delirium affects between 24% and 43% of patients, and negatively impacts patient outcomes. Recently, research attention has been on preventive interventions for delirium, with melatonin receptor agonists and orexin receptor ...
Yukiko Miyoshi, Yuki Shigetsura, Daiki Hira, Takakuni Maki, Hirotsugu Kawashima, Naoko Sugita, Noriko Sugawara, Noriaki Kitada, Machiko Hirai, Masayoshi Kawata, Hiroki Endo, Yusuke Kojima, Keiko Ikuta, Yurie Katsube, Natsuki Imayoshi, Shunsaku Nakagawa, Masahiro Tsuda, Tomohiro Terada   +17 more
doaj   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

THE TEACHING OF THERAPEUTICS AND PHARMACOLOGY FROM THE EXPERIMENTAL STANDPOINT. [PDF]

, 1902
TORALD SOLLMANN
openalex   +1 more source

Pharmacology and therapeutics

Current Opinion in Nephrology and Hypertension, 1992
Hans R. Brunner, John D. Bauer
openaire   +3 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source