Results 191 to 200 of about 1,549,234 (325)

Moving beyond shock: Rich-lean transition procedures as a modern approach to anxiolytic screening. [PDF]

J Pharmacol Exp Ther
Rough MI, Kratzenberg JL.
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Building Pharmacoequity through Student and Trainee Education, Service, and Global Outreach. [PDF]

Clin Pharmacol Ther
Riley C, Casas ND, Maglalang PD, Su H, Le A, Etrouth S, Killam SR, McRae M.   +7 more
europepmc   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

Advancing Pharmacoequity Globally: Reflections from the ASCPT Development, Regulatory, and Outcomes Network. [PDF]

Clin Pharmacol Ther
Jayachandran P, Ladumor MK, Vlasakakis G, Riselli A, Ilic KV, van Wijk RC, Elmeliegy M, Mukker JK, Sawant-Basak A, Long T, Dong J, Rayad N, Zhang T, DRO Network.   +13 more
europepmc   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Celebrating the 65th Anniversary of the Journal of Clinical Pharmacology. [PDF]

J Clin Pharmacol
van den Anker J.
europepmc   +1 more source

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

Advanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu, Mengsi Zhan, Haoyu Huang, Jianhong Wang, Cheng Ni, Xiaojun Zhou, Hannah Küttner, Cong Song, Xiangyang Shi, Andrij Pich   +9 more
wiley   +1 more source

Population Pharmacokinetic Analysis of MIT-001, a Novel Ferroptosis Inhibitor, for Dose Optimization. [PDF]

J Clin Pharmacol
Bae S, Kim E, Rhee SJ, Kim S, Yu KS, Lee S.   +5 more
europepmc   +1 more source

Perception of Medical and Nursing Students Plus Clinical Instructors Towards Objective Structured Clinical Examination: A Case Study of Five Health Training Institutions in Sub-Saharan Africa

Advances in Medical Education and Practice
Ronald Kibuuka,1 Ferestas Mpasa,2 Andrew Marvin Kanyike,1 Chizoma Millicent Ndikom,3 Atipatsa Chiwanda Kaminga,2 Samuel Owusu-Sekyere,4 Adenike Ogah,5 Abigail Kusi Amponsah,6 Kennedy Kiyimba,1 Samuel Baker Obakiro,1 Getrude Munthali,2 Wanangwa Kenneth ...
Kibuuka R, Mpasa F, Kanyike AM, Ndikom CM, Kaminga AC, Owusu-Sekyere S, Ogah A, Kusi Amponsah A, Kiyimba K, Obakiro SB, Munthali G, Msowoya WK, Kibuule D, Phiri EC, Baluwa M, Phiri T, Katuramu R   +16 more
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