Results 191 to 200 of about 429,144 (355)

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Editorial: Application of PKPD modeling in drug discovery and development. [PDF]

Front Pharmacol
Ren HC, Zhu X, Hao K, Le SY.
europepmc   +1 more source

Clinical pharmacology and therapeutics in the 1980s [editorial] [PDF]

, 1978
C. T. Dollery
openalex   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John, Caitlyn Dang, Nidhi Reddy, Calvin Chao, Karen J. Ho, Bin Jiang   +5 more
wiley   +1 more source

Perception of Medical and Nursing Students Plus Clinical Instructors Towards Objective Structured Clinical Examination: A Case Study of Five Health Training Institutions in Sub-Saharan Africa

Advances in Medical Education and Practice
Ronald Kibuuka,1 Ferestas Mpasa,2 Andrew Marvin Kanyike,1 Chizoma Millicent Ndikom,3 Atipatsa Chiwanda Kaminga,2 Samuel Owusu-Sekyere,4 Adenike Ogah,5 Abigail Kusi Amponsah,6 Kennedy Kiyimba,1 Samuel Baker Obakiro,1 Getrude Munthali,2 Wanangwa Kenneth ...
Kibuuka R, Mpasa F, Kanyike AM, Ndikom CM, Kaminga AC, Owusu-Sekyere S, Ogah A, Kusi Amponsah A, Kiyimba K, Obakiro SB, Munthali G, Msowoya WK, Kibuule D, Phiri EC, Baluwa M, Phiri T, Katuramu R   +16 more
doaj  

Deciphering the Relative Contribution of CYP3A4 Versus P-Glycoprotein for the Shared Substrate Cyclosporine-Commentary on Lown et al. [PDF]

Clin Pharmacol Ther
Cascorbi I, Kim RB.
europepmc   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Correction for: EpiAge: a next-generation sequencing-based <i>ELOVL2</i> epigenetic clock for biological age assessment in saliva and blood across health and disease. [PDF]

Aging (Albany NY)
Cheishvili D, Carmo SD, Caraci F, Grasso M, Cuello AC, Szyf M.   +5 more
europepmc   +1 more source

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Leading the Way: Multi-Drug Resistance Protein (MDR1) and Clinical Pharmacology-Commentary on Kim et al. [PDF]

Clin Pharmacol Ther
Giacomini KM.
europepmc   +1 more source