Results 191 to 200 of about 425,132 (355)

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han   +7 more
wiley   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski   +3 more
wiley   +1 more source

Perception of Medical and Nursing Students Plus Clinical Instructors Towards Objective Structured Clinical Examination: A Case Study of Five Health Training Institutions in Sub-Saharan Africa

open access: yesAdvances in Medical Education and Practice
Ronald Kibuuka,1 Ferestas Mpasa,2 Andrew Marvin Kanyike,1 Chizoma Millicent Ndikom,3 Atipatsa Chiwanda Kaminga,2 Samuel Owusu-Sekyere,4 Adenike Ogah,5 Abigail Kusi Amponsah,6 Kennedy Kiyimba,1 Samuel Baker Obakiro,1 Getrude Munthali,2 Wanangwa Kenneth ...
Kibuuka R   +16 more
doaj  

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis   +6 more
wiley   +1 more source

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