Results 201 to 210 of about 1,302,607 (412)
Advances in pharmacology and therapeutics [PDF]
British Journal of Anaesthesia, 2009 Philip M. Hopkins, Jonathan G. Hardman
openaire +3 more sources
Optimal Control For Anti-Abeta Treatment in Alzheimer's Disease using a Reaction-Diffusion Model [PDF]
arXivAlzheimer's disease is a progressive neurodegenerative disorder that significantly impairs patient survival and quality of life. While current pharmacological treatments aim to slow disease progression, they remain insufficient in halting cognitive decline.
arxiv
Skeletal MuscleIntramuscular fat (IMAT) infiltration, pathological adipose tissue that accumulates between muscle fibers, is a shared hallmark in a diverse set of diseases including muscular dystrophies and diabetes, spinal cord and rotator cuff injuries, as well as ...
Alessandra M. Norris +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
CreoPep: A Universal Deep Learning Framework for Target-Specific Peptide Design and Optimization [PDF]
arXivTarget-specific peptides, such as conotoxins, exhibit exceptional binding affinity and selectivity toward ion channels and receptors. However, their therapeutic potential remains underutilized due to the limited diversity of natural variants and the labor-intensive nature of traditional optimization strategies. Here, we present CreoPep, a deep learning-
arxiv
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source