Results 181 to 190 of about 1,429,081 (399)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Aumento del uso de nuevos antipsicóticos en niños: ¿Debemos preocuparnos?

open access: yesEvidencia. Actualización en la Práctica Ambulatoria, 2010
nan Therapeutics Initiative
doaj   +1 more source

The NLRP3 inflammasome: molecular activation and regulation to therapeutics

open access: yesNature reviews. Immunology, 2019
Karen V. Swanson, Meng Deng, J. Ting
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Therapeutics [PDF]

open access: yes, 1952
ΔΕ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗNO ABSTRACT ...
Εταιρεία, Ελληνική Κτηνιατρική
core   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Emerging concepts of miRNA therapeutics: from cells to clinic.

open access: yesTrends in Genetics, 2022
C. Diener, A. Keller, E. Meese
semanticscholar   +1 more source

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