Results 221 to 230 of about 872,419 (247)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Therapeutics.

, 1878

openalex   +1 more source

DPP4 Inhibitors and Hypersensitivity Reactions: Experiences From Clinical Pharmacology and Diabetes and Allergy-Asthma Therapeutics Specialty Clinics

Shambo Samrat Samajdar, Shatavisa Mukherjee, Pudupakkam K. Vedanthan, Saibal Moitra, Santanu Kumar Tripathi, Banshi Saboo, Shashank Joshi   +6 more
openalex   +1 more source

Amivantamab Plus Lazertinib in Atypical <i>EGFR</i>-Mutated Advanced Non-Small Cell Lung Cancer: Results From CHRYSALIS-2. [PDF]

J Clin Oncol
Tomasini P, Wang Y, Li Y, Felip E, Wu L, Cui J, Besse B, Spira AI, Neal JW, Goto K, Baik CS, Marmarelis ME, Ichihara E, Zhang Y, Lee JS, Lee SH, Yang JC, Michels S, Anastasiou Z, Curtin JC, Lyu X, Mahoney J, Demirdjian L, Meyer CS, Zhang Y, Leconte I, Lorenzini P, Knoblauch RE, Trani L, Baig M, Bauml JM, Cho BC, CHRYSALIS-2 Cohort C.   +32 more
europepmc   +1 more source

Supplementary Figure S4 from Gallium-68–labeled Peptide PET Quantifies Tumor Exposure of PD-L1 Therapeutics

Akhilesh Mishra, Dhiraj Kumar, Kuldeep Gupta, Gabriela Lofland, Ajay Sharma, Dhanush S. Banka, Robert F. Hobbs, Robert F. Dannals, Steven P. Rowe, Edward Gabrielson, Sridhar Nimmagadda   +10 more
openalex   +1 more source

First-in-human study of TN-201, an AAV9 gene replacement therapy in MYBPC3-associated hypertrophic cardiomyopathy: initial safety, pharmacodynamic, and imaging results from MyPEAK-1. [PDF]

Cardiovasc Res
Desai MY, Nagueh SF, Giudicessi JR, Previs MJ, Kellner D, Pollman MJ, Varfaj F, Robertson LA, Sonicheva-Paterson N, Pushkin R, Mangal B, Tomlinson L, Harrison WG, Yamamoto L, Argast G, Lombardi LM, Ivey KN, Tingley WG.   +17 more
europepmc   +1 more source