Results 111 to 120 of about 385,973 (351)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Decoding sensorimotor rhythms during robotic-assisted treadmill walking for brain computer interface (BCI) applications

, 2015
Locomotor malfunction represents a major problem in some neurological disorders like stroke and spinal cord injury. Robot-assisted walking devices have been used during rehabilitation of patients with these ailments for regaining and improving walking ...
Garcia Cossio, Dr. E.G.C. (Donders Institute for Brain, Cognition and Behavior)
core   +1 more source

Neuraltherapy Treatment of Shoulder Periarthritis: A Case Report

Medicine Science, 2015
In recent years, increasing importance worldwide has been given to treatment with natural methods, also known as complementary medicine. Currently, there are 18 sub-branches of treatment; neuraltherapy, acupuncture, phytotherapy, ozone therapy, manual ...
Tuba Tulay Koca
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Retinal arterioles narrow with increasing duration of anti-retroviral therapy in HIV infection: a novel estimator of vascular risk in HIV? [PDF]

, 2012
OBJECTIVES: HIV infection is associated with an increased risk of age-related morbidity mediated by immune dysfunction, atherosclerosis and inflammation.
Pathai, Sophia, Peto, Tunde; id_orcid, Tien Y Wong, Weiss, Helen A, Helen A Weiss, Colin Cook, Cook Colin, Tien Y. Wong, Tunde Peto, Lawn, Stephen D, Gilbert Clare E., Weiss Helen A., Wong Tien Y., Stephen D Lawn, Leris M D'Costa, Clare E. Gilbert, Peto Tunde, Sophia Pathai, Pathai Sophia, Leris M. D’costa, Lawn Stephen D., Cook, Colin, Helen A. Weiss, D’Costa Leris M., Gilbert, Clare E, Stephen D. Lawn, Peto, Tunde, Wong, Tien Y, D'Costa, Leris M, Clare E Gilbert   +29 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Using a Fuzzy Emotion Model in Computer Assisted Speech Therapy

, 2011
Affective computing – machine’s ability to recognize and simulate human affects – has become a main research field for Human Computer Interaction.
Schipor, Ovidiu Andrei, Ovidiu A. Schipor, Maria D. Schipor, Schipor, Maria Doina, Pentiuc, Stefan Gheorghe, Stefan G. Pentiuc   +5 more
core   +1 more source

Computer-Assisted Analysis of Oral Antifungal Therapy In Chronic Rhinosinusitis With Airway Mycosis: A Retrospective Cohort Analysis

, 2021
Environmental fungi are etiologically related to chronic rhinosinusitis (CRS) with airway mycosis, but their infectious role remains uncertain, in part because of potentially inadequate methods of disease quantitation.
Luong, Amber U, Kheradmand, Farrah, Scheurer, Michael, Corry, David B, Li, Evan   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source