Results 171 to 180 of about 5,449,643 (269)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Retrospective analysis of cutaneous immune-related adverse events following checkpoint inhibitor therapy in melanoma patients reveals increased risk associated with the HLA-B*51:01 allele. [PDF]

Cancer
DiLeo M, Oglesby S, Leung CH, Pauken KE, Farooq S, Haydu LE, Kubicki SL, Martinez R, Welborn M, Zahiruddin S, Zou J, Cao K, Patel AB.   +12 more
europepmc   +1 more source

Cellular senescence imaging and senolysis monitoring in cancer therapy based on a β-galactosidase-activated aggregation-induced emission luminogen

Peili Cen, Chunyi Cui, Jiani Huang, Hetian Chen, Fei Wu, Jiaqi Niu, Yan Zhong, Chentao Jin, Weihong Zhu, Hong Zhang, Mei Tian   +10 more
openalex   +1 more source

Evaluation of the immunogenicity and impact on the latent HIV‐1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy‐treated subjects [PDF]

, 2017
Gemma Hancock, Sara Morón‐López, Jakub Kopycinski, María C. Puertas, Eleni Giannoulatou, Annie Rose, María Salgado, E Hayton, Alison Crook, Catharine Morgan, Brian Angus, Fabian Chen, Hongbing Yang, Javier Martínez‐Picado, Tomáš Hanke, Lucy Dorrell   +15 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Retracted: Fusion of Emotional Thinking and Mental Health of Students in Vocal Music Teaching

Occupational Therapy International
Occupational Therapy International
doaj   +1 more source

Effects of Antiplatelet and Anticoagulant Therapy on Emergency Surgical Outcomes in Orthopedic Trauma Patients With Cardiac Comorbidities. [PDF]

Cureus
Mashayekhi Y, Onsa M, Chadalavada G, Baba-Aissa S, Kakar S, Vinayak S, Younas S, Akram MZ, Qureshi MA, Shafique Ur Rehman M.   +9 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Hemodynamics-guided therapy for hypertensive disorders of pregnancy: a systematic review. [PDF]

Arch Gynecol Obstet
Loheit AC, Lößner C, Schleussner E, Groten T.   +3 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source