Results 41 to 50 of about 9,885,342 (364)
TREATMENTCINE THERAPY THERAPY CAOFCLEAICARBUNCLE [PDF]
Journal of the American Medical Association, 1911 The brilliant results produced by the use of Staphylococcus aureus vaccine in the treatment of carbuncles is already to well known to require further discussion. The following case, however, I am sure, is of sufficient interest to warrant reporting: History. —Mr. R., aged 48, had been suffering with diabetes for three years, during which time he had
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Journal of Thoracic Oncology, 2010 Even after complete surgical resection of pulmonary metastases, many patients develop recurrent disease in the thorax despite the use of systemic chemotherapy, dosage of which is limited because of systemic toxicity. Although subsequent operations are feasible and good long-term results have been reported, sufficient functional lung parenchyma must ...
van Schil, Paul +2 more
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Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
, 2015 Narrative therapy (NT) is a strengths-based approach to psychotherapy that uses collaboration between the client or family and the therapist to help clients see themselves as empowered and capable of living the way they want.
Rice, Robert H.
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Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
, 2017 PEOPLE\u27S CHOICE AWARD WINNER! We designed a solar powered hot plate that also functions as a light source. This allows refugees to cook food without burning wood or using toxic fuels and provides a portable light source. Nexus Maximus IV The Challenge:
Beauchner (Industrial Design), Adam +4 more
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Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
EMDR therapy for PTSD after motor vehicle accidents: meta-analytic evidence for specific treatment [PDF]
, 2015 Motor vehicle accident (MVA) victims may suffer both acute and post-traumatic stress disorders (PTSD). With PTSD affecting social, interpersonal and occupational functioning, clinicians as well as the National Institute of Health are very interested in ...
Boccia, Maddalena +4 more
core +1 more source
Journal of Law and the Biosciences, 2018 What, exactly, is "gene therapy"? Crystallizing a modern definition of "gene therapy" has now become critically important on several fronts. Following the recent of passage the 21st Century Cures Act, FDA now relies on the term to give regulatory incentives to sponsors of certain ‘regenerative medicines’, including ‘gene therapies’.
Jacob S. Sherkow +4 more
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