Results 51 to 60 of about 9,885,342 (364)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset +9 morewiley +1 more sourceEffects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial [PDF]
, 2019 Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy.Abano, Nenette, Abbdul-saheb, Mudhar, Adedoyin, Temi, Adell, Victoria, Adesina, Tolu, Adie, Katja, Adil-Smith, Jennifer, Ahmad, Nasar, Ahmed, Ashraf, Ahmed, Iman, Al-Mayhani, Talal, Al-Shahi Salman, Rustam, Al-Shahi Salman, Rustam, Alam, Mohammad Irfan, Albazzaz, Mo, Ali, Ali, Alipio, Francis, Allen, Christopher, Allison, Joanna, Amey, Isobel, Amis, Elaine, Amlani, Sageet, Amoils, Shannon, Amor, Kelly, Anderson, Rosemary, Andole, Sreeman, Anjum, Talat, Ankolekar, Sandeep, Annamalai, Arunkumar, Anthony, Alpha, Anversha, Ajmal, Anwar, Ijaz, Anwar, Sajjad, Appleton, Jason, Argandona, Lucia, Armitage, Jane, Ashton, Amy, Atkinson, Natalie, Auld, Grace, Avis, Joanne, Aweid, Basaam, Ayres, Georgina, Azhar, Khalid, Bagnall, Caroline, Baig, Farrukh, Baigent, Colin, Bailey, Duncan, Baird, Yolanda, Bakawala, Rehana, Baker, John, Baker, Pauline, Balazikova, Olga, Balian, Linda, Baliga, Vidya, Balitska, Olesia, Ball, Julie, Ball, Margaret, Ballantine, Robert, Bamford, John, Banaras, Azra, Barber, Mark, Barbon, Emma, Barker, James, Barr, Charlotte, Barrie, Elizabeth, Barron, Luke, Barry, Adrian, Bateman, Gavin, Bates, Michelle, Bathula, Rajaram, Battersby-Wood, Emma, Bayliss, Pauline, Beadle, Hannah, Bearne, Helen, Beaty, Teresa, Beaves, Emily, Bell, Angela, Bell, Jo, Bell, Murdina, Bellfield, Ruth, Beranova, Eva, Bergin, Adrian, Bhakri, Harbens, Bhalla, Ajay, Bharaj, Kiranjit, Bhargava, Maneesh, Bhaskaran, Biju, Bhatnagar, Priya, Bhatnagar, Priya, Birchall, Kathryn, Birns, Jonathan, Black, Toby, Blades, Alex, Blair, Caroline, Blair, Caroline, Blair, Gordon, Blane, Sujata, Blank, Catrin, Blight, Adrian, Board, Joanne, Board, Sarah, Bokhari, Maria, Bond, Kirsty, Bowring, Angela, Boxall, Cherish, Breeds, Joanna, Brew, Helen, Brezitski, Maria, Bridger, Hayley, Brodie, Fiona, Brotherton, Lucy, Broughton, David, Brown, Claire, Brown, Ellen, Brown, Pauline, Brown, Sarah, Bruce, David, Buchanan, David, Buck, Amanda, Buckle, Steve, Buckle, Steve, Buckley, Clare, Bunea, George, Burger, Ilse, Burgess, Laura, Burgess, Seona, Burssens, Evelyne, Butler, Adrian, Butler, Donna, Butler, Rebecca, Butterworth-Cowin, Nicola, Button, Denise, Buxton, Jean, Byrne, Anthony, Cageao, Julie, Caine, Sarah, Campbell, Robert, Carpenter, Michael, Carpio, Racquel, Carrie, Johanna, Cassidy, Tim, Causley, Chelsea, Chadbourn, Indra, Chadha, Dinesh, Chamberlain, Angela, Chan, kelly, Chandrakumar, Aberami, Chapman, Kath, Chapman, Nicola, Charles, Bethan, Chatterjee, Kausic, Chaudhry, Afnan, Chauhan, Meena, Chenna, Srikanth, Cherian, Suja, Cheripelli, Bharath Kumar, Chopra, Neha, Choulerton, James, Choy, Lillian, Clarke, Brian, Clarke, Caroline, Clarke, Judith, Clarke, Natasha, Clarke, Rebecca, Clarke, Samantha, Clarkson, Emma, Clay, Caroline, Clayton, Susan, Clayton-Evans, Lisa, Cluckie, Gillian, Cochrane, Helen, Codd, Laura, Cohen, David, Collins, Kayleigh, Connor, Lynda, Constantin, Carmen, Cook, Angela, Cooper, Martin, Copeland, Claire, Cosier, Tracey, Courtauld, Gillian, Couser, Mandy, Coward, Lucy, Cowie, Linda, Cox, Chantel, Cox, Chloe, Cox, Penelope, Crabtree, Karen, Crawford, Pam, Crawford, Susan, Creeden, Robyn, Crisp, Sarah, Cronin, Julie, Crook, Luci, Crosbie, Caroline, Crouch, Nichola, Crown, Rachel, Crowther, Hannah, Cuddy, Sarah, Cuenoud, Larissa, Cullen, Claire, Culmsee, Charlotte, Cunningham, James, Cunningham, Mishell, Cvoro, Vera, Dacey, Lynne, Dakin, Katy, Dallol, Bander, Dangri, Puneet, Datta, Prabal, Davey, Richard, David, Anette, David, Owen, Davies, Caroline, Davies, Ruth, Davies, Silvie, Davis, Fiona, Davis, Michelle, Day, Nicola, Dayal, Nilofer, De Berker, Henry, Deary, Ann, Denic, Hayley, Dennis, Martin, Dennis, Martin S, Denniss, Carol, Devine, Joseph, Devitt, Nicola, Dewar, Richard, Dhakal, Mahesh, Dhar, Saikat, Dickinson, Christina, Dickson, Christine, Dima, Sofia, Dinsmore, Lynn, Dixon, Lynn, Dobson, Tracey, Dodd, Angela, Dodd, Emily, Doherty, Mandy, Doherty, Mandy, Donaldson, Denise, Donnelly, Richard, Doubal, Fergus, Dow, Lindsey, Downham, Susan, Doyle, Clare, Doyle, Donna, Drever, Jonathan, du Plessis, Johann C, du Plessis, Johannes, Dube, Judith, Duberley, Stephen, Dunn, Linda, Dunne, Karen, Durairaj, Ramesh, Durman, Helen, Dutta, Dipankar, Dynan, Kevin, Edwards, Mandy, Egerton, Shuna, Eglinton, Charlotte, Eglinton, Charlotte, El Tawil, Salwa, Elfandi, Khaled, Elliot, Jennifer, Elliott, Emma, Ellis, Sam, Emberson, Jonathan, Emsley, Hedley, England, Timothy, Epstein, Daniel, Erande, Renuka, Erumere, Esther, Esisi, Bernard, Esisi, Bernard, Esson, Derek, Esson, Derek, Evans, Rachel, Evans, Sue, Eveson, David, Ewing, Jordan, Fathima, Razik, Fawcett, Michelle, Feerick, Shez, Fennelly, Ruth, Ferdinand, Phillip, Findlay, Paul, Finlay, Sarah, Finney, Kay, Fitzell, Pauline, Fitzsimmons, Paul, Fletcher, Glyn, Fletcher, Jo, Fong, Rosanna, Foot, Jayne, Foote, Leanne, Ford, Gary, Foster, Eliza, Fotherby, Ken, Fox, Charlotte, Francia, Nina, Francis, Jobbin, Fraser, Ruth, Fraser, Ruth, Fuller, Tracy, Fulton, Ailsa, Furnace, Jacqueline, Gadapa, Naveen, Gainard, Glyn, Gainsborough, Nicola, Gallagher, Jill, Gallagher, Louise, Gallifent, Rachel, Gamble, Ed, Garcia, Tatiana, Gardener, Léjeune, Garfield-Smith, Joanne, Garside, Mark, Gartrell, Imogen, Gascoyne, Rachel, Gattringer, Thomas, Gautam, Nikki, Gaylard, Jane, Gbadamoshi, Lukuman, Geraghty, Olivia, Ghaly, George, Ghatala, Rita, Ghosh, Sandip, Giallombardo, Elio, Gilham, Ellie, Gilmour, Danielle, Gilzeane, Nicola, Glass, Jon, Gleave, Laura, Glover, Rachel, Godfrey, Margi, Goff, Anita, Goorah, Neetish, Gott, Valerie, Gow, Heather, Graham, Carol, Graham, Ruth, Gray, Jane, Green, Carole, Greenwood, Richard, Gregory, Bindu, Greig, Jill, Grimwood, Gemma, Grocott, Jeanette, Grue, Rebecca, Gulliver, Diane, Guo, Fenglin, Gupwell, Karin, Guthrie, Lucy Belle, Guy, Helen, Guyler, Paul, Hague, Adam, Haider, Syed, Hairsine, Brigid, Hakim, Eluzai, Hall, Andrea, Halse, Omid, Handley, Dominic, Hann, Gail, Hannon, Niamh, Hansen, Christian, Haque, Mohammad, Hardwick, Anne, Harkness, Kirsty, Harrington, Frances, Harrington-Davies, Yasmin, Harrison, Louise, Harrison, Melanie, Harrison, Thomas, Harston, George, Harvey, Kirsten, Harvey, Miriam, Hassan, Ahamad, Hassan, Hardi, Havard, Diane, Hayes, Anne, Hayhoe, Helen, Hayman, Rachel, Hays, Carole, Hazel, Beth, Hedstrom, Amanda, Hedstrom, Amanda, Hemsley, Anthony, Henry, Margo, Herman, Jane, Hervey, Simon, Hewitt, Jonathan, Hiden, Joanne, Hogan, Caroline, Hogg, Valerie, Holden, Melinda, Holmes, Clare, Homan, Jane, Hooley, Michaela, Horan, Kathleen, Horton, Sarah, Hostettler, Isabel, Hove, Dionne, Howaniec, Laura, Howard, Gabriella, Howard, Joanne, Howard, Peter, Howcroft, Deborah, Howe, Jo, Huang, Xuya, Huggett, Isabel, Hughes, Chloe, Hughes, Claire, Hughes, Tom, Humphreys, Louise, Humphries, Fiona, Hunt, Benjamin, Hunt, Nicholas, Hunter, Annemarie, Hunter, Neil, Hurford, Frances, Hurley, Jennifer, Hussain, Malik, Hutchison, Aidan, Hyams, Benjamin, Hyatt, Lisa, Imam, Javed, Ingham, Andrea, Ingram, Tanya, Innes, Karen, Iqbal, Arshi, Iqbal, Mohammad Shazad, Irvine, Janice, Ispoglou, Sissy, Ivatts, Simone, Jackson, Benjamin, Jackson, Linda, Jagger, Jenny, Jagpal, Baljit, James, Ali, James, Claire, James, Martin, Jarapa, Rowilson, Jarrett, David, Jeffs, Carol, Jelley, Benjamin, Jenkins, Colin, Jennings-Preece, Karla, Jeyaraj, Naomi, Jha, Ratneshwari, Jinks, Emma, Johnes, Mary, Johnson, Sharon, Jones, Ifan, Jones, Ifan, Jones, Kirsty, Jones, Rachael, Jones, Stephanie, Jones, Terry, Jones, Val, Jordan, Carla, Jose, Deepa, Jose, Josin, Joshi, Yogish, Joshi, Yogish, Joyson, Anu, Jupp, Becky, Justin, Frances, Kakar, Puneet, Kalathil, Latheef, Kalladka, Dheeraj, Kamara, Christine, Kambafwile, Mary, Kane, Ingrid, Kar, Arindam, Keegan, Breffni, Keeling, Elizabeth, Keenan, Samantha, Kelavkar, Shyam, Kelly, Christine, Kelly, Debs, Kelly, Jim, Kelly, Siobhan, Keltos, Marketa, Kennedy, James, Kennedy, Kate, Kenton, Antony, Kerin, Lourda, Kerr, Enda, Kerr, Gillian, Keshvara, Rekha, Khan, Mohammad, Khan, Shagufta, Khan, Usman, Khan, Uzma, Kibutu, Faith, King, Sam, Kingwell, Hayley, Kini, Manohar, Klaasen, Katrina, Knops, Kerstin, Krishnamoorthy, Shrivakumar, Krishnamurthy, Ramesh, Krishnamurthy, Vinodh, Krishnan, Kailash, Krishnan, Manju, Krommyda, Magdalini, Kullane, Sagal, Kumar, Balakrishna, Kumar, Pradeep, Kunhunny, Swapna, Lam, Man Yee, Lambert, Caroline, Landers, Geraldine, Langhorne, Peter, Lasserson, Daniel, Latter, Laura, Law, Zhe, Lawrence, Tara, Lawson, Heidi, Leason, Sandra, Lee, Stephanie, Leggett, Jacqui, Lenti, Giulia, Lerpiniere, Christine, Lerpiniere, Christine, Licenik, Radim, Lindert, Ralf, Little, Victoria, Littleton, Edward, Ljubez, Anja, Loganathan, Thayalini, Longland, Barbara, Lopez, Paula, Lovelock, Caroline, Lowe, Gordon, Lucas, Linda, Lucas, Suzanne, Luder, Robert, Lyjko, Sue, Maanoosi, Mehran, Maatouk, Ahmad, Macaden, Ashish, MacInnes, Brian, MacLennan, Beverly, Macleod, Malcolm, MacLeod, Mary, MacLiver, Linda, MacRaild, Allan, Maddula, Mohana, Madigan, Barbara, Maguire, Holly, Maguire, Stuart, Maiden, Susan, Majis, Arshad, Majmudar, Nikhil, Makawa, Linetty, Mangion, David, Manning, Lisa, Manoj, Aravind, Mardania, Rina, Marigold, James Richard, Markova, Skarlet, Marks, Katherine, Marsden, Tracy, Marshall, Sally, Martin, Irene, Mashate, Sheila, Mason, Cathy, Mate, Abhijit, Mathieson, Philip, Matias, Oliver, Matthews, Christopher, Maund, Bev, McAlpine, Christine, McArdle, Damian, Mcauley, Sean, McCann, Stephanie, McCarron, Mark, McClelland, Beverley, McCormick, Katrina, McCormick, Katrina, McDonald, Shanni, McDonald, Susan, Mcgee, Joanne, McGhee, Caroline, McGill, Connor, McGrath, Aileen, McIlmoyle, James, McKee, Jacqueline, McLoughlin, Alison, McVerry, Ferghal, Mead, Denise, Mead, Gillian, Meir, Julie, Menon, Nisha, Mercer, Lily, Metcalf, Kneale, Miller, Keniesha, Miller, Richard, Milligan, Josette, Minks, David, Minks, David P., Miriam, Skelton, Mistri, Amit, Mitchell, Jennifer, Mitra, Dipayan, Mitra, Dipayan, Mohammed, Niaz, Mohd Nor, Azlisham, Mokoena, Betty, Moores, Andrew, Moqsith, Mohammed, Morell, Jordi, Moreton, Fiona, Morgan, Debbie, Moroney, Helen, Morse, Bethan, Moseley, Sally, Motherwell, Nichola, Moynihan, Barry, Mpelembue, Mushiya, Mudd, Paul, Muddegowda, Girish, Muir, Keith, Mukherjee, Indranil, Murali, Elodie, Murphy, Peter, Murray, Gordon D, Musarrat, Kashif, Myint, Min, Naeem, Muhammad, Naing, Zin, Nair, Anand, Nallasivan, Arumugam, Nasar, Mohammad, Nasim, Ashraf, Naylor, Charde, Needle, Ann, Nelson, Sandra, Newby, David E, Newton, Sophie, Ng, Kheng Xiong, Ngo, David, Nguyen, Vinh, Ngwako, Mmua, Ni, Hlaing, Nicholas, Paul, Nicolson, Anne, Niranchanan, Rangah, Nisar, Nabeela, Njoku, Kelechi, Nott, Claire, Nott, Claire, Nozedar, Tarn, Nyabadza, Sheila, O'Brien, Eoin, O'Brien, Richard, O'Brien, Richard, O'Connell, Susan, O'Loughlin, Victoria, O'Reilly, Joanna, O'Toole, Sarah, OConnell, Janice, Oji, Nnebuife, Orath Prabakaran, Rajalakshmi, Orefo, Chukwuka, Orugun, Enoch, Osborn, Mairead, Osborne, Emily, Oshodi, Anne, Osman, Ahmed, Ovington, Catherine, Owings, Paula, Owoyele, Emmanuelle, Owusu-Agyei, Peter, Pai, Yogish, Palmer, Jeb, Papavasileiou, Vasileios, Parakramawansha, Ruwan, Parker, Richard, Parry, Anthea, Parry-Jones, Adrian, Pasco, Kath, Patel, Bhavini, Patel, Champa, Patel, Farzana, Patel, Krishna, Patterson, Chris, Paulton, Ruth, Pawley, Corinne, Peixoto, Cassilda, Penge, Justin, Perez, Jane, Perfitt, Rebekah, Perkins, Charlotte, Perry, David, Perry, Jack, Persad, Nicola, Peters, Jenny, Pettitt, Kerry, Phiri, Duke, Pitt-Ford, Alexandra, Pitt-Kerby, Tressy, Plewa, Catherine, Poku, Philip, Ponnambath, Suheil, Poultney, Una, Pound, Susan, Power, Michael, Pressly, Vanessa, Price, Fiona, Proeschel, Harald, Punekar, Shuja, Punter, Martin, Pusalkar, Aparna, Putterill, Janet, Quinn, Leanne, Quinn, Outi, Qureshi, Sammie, Ragab, Suzanne, Raghunathan, Senthil, Rahman, Bithi, Rai, Baljinder, Raj, Sonia, Rajapakse, Anoja, Rajkumar, Chakravarthi, Ramachandran, Sankaranarayana, Ramadan, Hawraman, Ramshaw, Alex, Rana, Pratap, Randall, Marc, Rashed, Khalid, Rashmi, Sindhu, Ravenhill, Garth, Rayessa, Rayessa, Reckless, Ian, Reddan, Julie, Reddan, Julie, Redgrave, Jessica, Redjep, Ozlem, Remegoso, Alda, Richard, Bella, Richards, Emma, Rinkel, Gabriel, Roberts, Josh, Robinson, Matthew, Robinson, Naomi, Rodgers, Alicia, Rodrigues, Mark A, Rodriguez, Aryelly, Roffe, Christine, Roffe, Jack, Roganova, Tatjana, Rogers, Emily, Rogers, Gill, Rojas, Javier, Ross, Sarah, Roughan, Caroline, Rudd, Tony, Rudenko, Hannah, Saada, Janak, Saastamoinen, Kari, Sajid, Mahmud, Sakka, Eleni, Salehin, Maqsud, Salek-Haddadi, Afraim, Salih, Isam, Sally, Moore, Sandercock, Peter A G, Sangombe, Mirriam, Sangster, Graeme, Sanyal, Ranjan, Sarah, Procter, Sarah, Procter, Sattar, Naweed, Sattar, Saira, Saulat, Afaq, Saulat, Afaq, Schofield, Christine, Schulz, Ursula, Schumacher, Natasha, Schwarz, Stefan, Seagrave, Samantha, Sekaran, Lakshmanan, Sesay, Juliana, Sethuraman, Sakthivel, Shackcloth, Daniela, Shah, Alex, Shah, Sweni, Shahmehri, Shahrzad, Sharma, Nikhil, Sharpe, Simon, Shaw, Kelly Marie, Shaw, Louise, Sheikh, Saima, Shekhar, Raj, Shelton, Faye, Shinh, Naval, Shread, Ian, Shukla, Avani, Siddegowda, Prasad, Siddiq, Muhammad, Siddiqui, Amber, Siddiqui, Anwer, Sigsworth, Andrew, Simon, Rohan, Sims, Don, Singh, Arun, Sinha, Devesh, Skinner, Helen, Slade, Peter, Smart, Amanda, Smith, Andrew, Smith, Fiona, Smith, Gemma Marie, Smith, Simon, Smith, Wilma, Smyth, Nigel, Spencer, Jayne, Sprigg, Nikola, Sprigg, Nikola, Srinivasan, Meena, Stafford, Samantha, Stafford, Samantha, Stanners, Andrew, Steele, Amy, Stephen, Jacqueline, Stephens, Claire, Stevens, Angela, Stevens, Stephanie, Stevenson, Sarah, Stewart, Kelvin, Stocks, Kathy, Stone, Andrew, Storton, Sharon, Strain, David, Subramonian, Santhosh, Sudlow, Cathie, Sudlow, Cathie L M, Sukdeo, Varthi, Sullivan, Frank, Sultan, Sulaiman, Suttling, Anne, Sutton, Claire, Sutton, Patrick, Sutton, Victoria, Sword, Jane, Sykes, Lucy, Symonds, Stuart, Szabo, Susan, Tallantyre, Emma, Tanate, Alfonso, Tandy, Jane, Tate, Margaret, Tauro, Suzanne, Tayler, Michelle, Taylor, Pat, Taylor, Vicky, Teal, Rachel, Temple, Natalie, Thant, Hlaing, Thavanesan, Kamy, Thomas, Isobel, Thomas, Kelly, Thomas, Philip, Thomas, Sarah, Thompson, Philip, Thompson, Susan, Thompson, Teresa, Thompson-Jones, Helen, Thomson, Audrey, Thornthwaite, Sarah, Thorpe, Kevin, Tilley, Victoria, Tiwari, Divya, Tomlin, Dawn, Tomlinson, Benjamin, Treadwell, Shelley, Tribbeck, Michele, Trippier, Sarah, Triscott, Claire, Triscott, Claire, Tryambake, Dinesh, Tucker, Laura, Tucker, Susan, Turfrey, Jennifer, Tysoe, Sharon, Ullah, Khalil, Valentine, Stacey, van Someren, Chloe, Varquez, Resti, Vasileiadis, Evangelos, Vassallo, Joseph, Venter, Marius, Veraque, Emelda, Verrion, Anna, Vettimootal Johnson, Venetia, Vickers, Carinna, Walford, Jamie, Walker, Allan, Walker, Marion, Walker, Pauli, Walker, Susannah, Wallace, Aine, Wallace, Rebecca, Wallace, Rebecca, Walstow, Deborah, Walter, Deborah, Walters, Ashleigh, Wani, Mushtaq, Ward, Deborah, Wardlaw, Joanna M, Watchurst, Caroline, Waterfield, Kelly, Waterfield, Kelly, Watson, Fran, Waugh, Dean, Webb, Tom, Webber, Adam, Webster, Timothy, Weinling, Marie, Weir, Nic, Weir, Pauline, Welch, Angela, Werring, David, Werring, David J, Whitcher, Alison, White, James, White, Julie, White, Philip M, White, Susan, Whiteley, William, Whiteley, William N, Whiteman, Jessica, Whiteman, Jessica, Whiting, Robert, Whittamore, Katherine, Wiggam, Ivan, Wilding, Peter, Wilkes, Gwendoline, Wilkinson, Mark, Willberry, Angela, Williams, Carol, Williams, Rebecca, Williams-Yesson, Barbara, Willmot, Mark, Wilson, David, Wilson, Duncan, Wilson, Jenny, Wilson, Lisa, Wilson, Sarah, Wiltshire, Alison, Wood, Diane, Wood, Edith, Wood, Lisa, Woodward, Stephen, Wright, Fiona, Wroath, Belinda, Wynter, Inez, Yadava, Rajendra, Yip, Brigitte, Young, Andrew, Zachariah, George, Zahoor, Tajammal, Zoe, Mellor +966 morecore +5 more sourcesEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceA prospective randomized trial of FK506-based immunosuppression after renal transplantation [PDF]
, 1995 A group of 204 adult patients was entered into a prospective, randomized trial comparing FK506/pred-nisone with FK506/azathioprine/prednisone after renal transplantation between August 1, 1991 and October 11,1992.Demetris, AJ, Fung, JJ, Hakala, TR, Irish, W, Jordan, ML, McCauley, J, Mitchell, S, Randhawa, P, Scantlebury, VP, Shapiro, R, Simmons, RL, Starzl, TE, Vivas, C +12 morecore +1 more sourceBiophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin +5 morewiley +1 more sourceHepatocyte growth factor gene therapy reduces ventricular arrhythmia in animal models of myocardial ischemia. [PDF]
, 2005 It was recently reported that gene therapy using hepatocyte growth factor (HGF) has the potential to preserve cardiac function after myocardial ischemia. We speculated that this HGF gene therapy could also prevent ventricular arrhythmia.Aoki, Motokuni, Hashimoto, Katsushi, Kaneda, Yasufumi, Kusano, Kengo Fukushima, Morishita, Ryuichi, Nakamura, Kazufumi, Ohe, Tohru, Yumoto, Akihisa +7 morecore +1 more source4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim +7 morewiley +1 more sourceOrganoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.Carla Ríos Arceo, Jarno Drostwiley +1 more source
