Results 81 to 90 of about 2,385,621 (262)

Criminal background check for initial massage therapy license

open access: yes, 2023
Effective January 1, 2024, all applicants applying for a massage therapy license with the SC Board of Massage Therapy will be subject to a state and national fingerprint criminal background ...
South Carolina Board of Massage Therapy
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The physical therapy and society summit (PASS) meeting: observations and opportunities [PDF]

open access: yes, 2010
journal articleThe construct of delivering high-quality and cost-effective health care is in flux, and the profession must strategically plan how to meet the needs of society.
Kigin, Colleen M.; Rogers, Mary M.; Wolf, Steven L.   +1 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

AT newsletter

open access: yes
Annual; Electronic coverage as of Dec. 26, 2003: Fall 2001-; Description based on: Vol. 5, no. 1 (fall 2001); Running title used (viewed Dec. 29, 2003).; Vol. 5, no.
Ohio Occupational Therapy, Physical Therapy, and Athletic Trainers Board. Athletic Trainers Section.
core   +3 more sources

Neuroimaging Applications for the Delivery and Monitoring of Gene Therapy for Central Nervous System Diseases

open access: yes
Neurological disease due to single gene defects represents a targetable entity for adeno-associated virus (AAV) mediated gene therapy. The delivery of AAV-mediated gene therapy to the brain is challenging, owing to the presence of the blood-brain barrier.
Vardar, Zeynep   +6 more
core   +1 more source

WORKING TOWARDS HEALTH EQUITY IN OCCUPATIONAL THERAPY

open access: yes, 2020
This study describes how health equity approaches are currently enacted in occupational therapy practice and documents barriers and needs to foster the integration of these approaches. Over 360 Canadian occupational therapists completed a survey based on
Rochefort-Allie, Charlène
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