Results 131 to 140 of about 4,145,262 (262)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Press Release: Optimization Systems Associates Inc. a key participant in Raytheon/Texas Instruments Joint Venture MIMIC Program [PDF]

open access: yes, 1988
Under subcontract to Compact Software Inc., Optimization Systems Associates Inc. is playing a key role in the MIMIC Program's Design Technology in the area of enhanced circuit optimization with tolerances.
Bandler, John W.
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Optimization of drug therapy in elderly individuals admitted to a geriatric unit

open access: yesClinical Interventions in Aging, 2017
Antoine Piau,1 Yoann Huet,1 Adeline Gallini,2,3 Laurine Andre,1–3 Bruno Vellas,1–3 Fati Nourhashemi1–3 1Gérontopôle, Centre Hospitalier Universitaire Toulouse, Toulouse, France; 2UMR1027, INSERM-University of Toulouse ...
Piau A   +5 more
doaj  

Exploring the neuromagnetic signatures of cognitive decline from mild cognitive impairment to Alzheimer's disease dementiaResearch in context

open access: yesEBioMedicine
Summary: Background: Developing non-invasive and affordable biomarkers to detect Alzheimer's disease (AD) at a prodromal stage is essential, particularly in the context of new disease-modifying therapies.
Sinead Gaubert   +9 more
doaj   +1 more source

Bacterial infectiogy, what role for phage therapy?

open access: yes, 2007
The role of Bacteriophage ...
CAPPARELLI, ROSANNA
core  

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Multicriteria Optimization in a Typical Multi-Isle Warehouse with Multiple Racks

open access: yes, 2014
14 páginasThis paper considers two common problems frequently found in warehouses: slotting and picking. The former refers to the best arrangement of items in the warehouse, while the latter concerns the definition of the best route to pick up the ...
Ramirez Rios, Diana G.   +5 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

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