Results 21 to 30 of about 4,145,262 (262)

Impact of perioperative hemodynamic optimization therapies in surgical patients: economic study and meta-analysis

open access: yesBMC Anesthesiology, 2020
Background Several studies suggest that hemodynamic optimization therapies can reduce complications, the length of hospital stay and costs. However, Brazilian data are scarce.
João M. Silva-Jr   +9 more
doaj   +1 more source

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]

open access: yes, 2022
In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
core   +1 more source

Ventriculoventricular delay optimization of a cardiac resynchronization device

open access: yesJournal of Arrhythmia, 2014
Cardiac resynchronization therapy (CRT) has become a standard option for patients with severe low cardiac function and mild to severe heart failure.
Koichi Sagara, MD
doaj   +1 more source

Impact of heterogeneities on lateral penumbra in uniform scanning proton therapy [PDF]

open access: yes, 2013
Purpose: In the treatment planning of uniform scanning proton therapy, an aperture block is designed for each beam with a margin, which typically includes the lateral penumbra measured in water (homogenous) medium.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City   +1 more
core   +1 more source

Endometrial polyps: optimization of anti-inflammatory therapy

open access: yesРепродуктивная эндокринология, 2018
The frequency of hyperproliferative pathology of endometrium is about 60–70% in the structure of gynecological pathology of postmenopausal women. Endometrial polyps are a fairly frequent gynecological pathology for women of all ages, but the overwhelming
Т. Ф Татарчук   +3 more
doaj   +1 more source

The Control Parametrization Enhancing Technique for Multi-Objective Optimal Control of HIV Dynamic [PDF]

open access: yesControl and Optimization in Applied Mathematics, 2016
In this paper, a computational approach is adopted for solving a multi-objective optimal control problem (MOOCP) formulation of optimal drug scheduling in human immunodeficiency (HIV) virus infected by individuals.
Hassan Zarei
doaj  

Neighborhood Optimization for Therapy Decision Support

open access: yesCurrent Directions in Biomedical Engineering, 2019
This work targets the development of a neighborhood-based Collaborative Filtering therapy recommender system for clinical decision support. The proposed algorithm estimates outcome of pharmaceutical therapy options in order to derive recommendations. Two
Gräßer Felix   +2 more
doaj   +1 more source

Optimal therapy for thymoma

open access: yesThe Journal of Medical Investigation, 2008
Thymoma is the most common tumor of the anterior mediastinum. This tumor is associated with unique paraneoplastic syndromes (myasthenia gravis, pure red cell aplasia, hypogammaglobulinemia, and other autoimmune diseases). The rarity of this tumor has somewhat obscured the optimal treatment. Although the histologic classification of thymoma has remained
openaire   +3 more sources

Importance of timing optimization for closed-loop applications of vagus nerve stimulation

open access: yesBioelectronic Medicine, 2023
In recent decades, vagus nerve stimulation (VNS) therapy has become widely used for clinical applications including epilepsy, depression, and enhancing the effects of rehabilitation.
Ramanamurthy V. Mylavarapu   +5 more
doaj   +1 more source

Dose optimization strategy of the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib for chronic myeloid leukemia: From clinical trials to real-life settings

open access: yesFrontiers in Oncology, 2023
With the advent of tyrosine kinase inhibitors (TKIs), the treatment prospects of chronic myeloid leukemia (CML) have changed markedly. This innovation can lengthen the long-term survival of patients suffering from CML. However, long-term exposure to TKIs
Fang Cheng   +10 more
doaj   +1 more source

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