Results 21 to 30 of about 9,648,016 (296)

Thermal design and experimental verification of the space ultraviolet wide field of view multi-channel scanning imager

open access: yesCase Studies in Thermal Engineering
In order to ensure the optimal imaging quality of the space ultraviolet wide field of view multi-channel scanning imager, it is imperative to conduct a comprehensive investigation into the thermal control system. First, we shall present the structure and
Renxin Wang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Thermal design, analysis and test: Framework for CubeSat in low Earth orbit

open access: yesResults in Engineering
Effective thermal control is crucial for ensuring the reliable of spacecraft subsystems in the space environment. This paper presents a comprehensive framework for the thermal design, analysis, and testing of CubeSats, highlighting the importance of each
Narimane Blanchete, Abdellah Bah
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Performance evaluation of the variable refrigerant flow (VRF) air-conditioning system subjected to partial and unbalanced thermal loadings

open access: yesJournal of Thermal Science and Technology, 2016
This paper shows the performance evaluation of the variable refrigerant flow (VRF) air-conditioning system subjected to partial and unbalanced thermal (cooling and heating) loadings.
Napoleon ENTERIA   +4 more
doaj   +1 more source

Degradation of Epoxy–Particles Composites Exposed to UV and Gamma Radiation

open access: yesChemistry, 2023
In the design and fabrication of any structural system for space application, balance between mass, stiffness and strength is crucial. Structures in space environments are exposed to high radiation levels and thermal shock, due to the sun irradiance and ...
Mauricio Torres   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An integrated model of soil-canopy spectral radiances, photosynthesis, fluorescence, temperature and energy balance [PDF]

open access: yes, 2009
This paper presents the model SCOPE (Soil Canopy Observation, Photochemistry and Energy fluxes), which is a vertical (1-D) integrated radiative transfer and energy balance model. The model links visible to thermal infrared radiance spectra (0.4 to 50 μm)
Su, Z   +17 more
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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