Results 41 to 50 of about 268,967 (357)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Beneficial Effect of Pt and of Pre-Oxidation on the Oxidation Behaviour of an NiCoCrAlYTa Bond-Coating for Thermal Barrier Coating Systems [PDF]

, 2011
The oxidation behaviour of a thermal barrier coating (TBC) system is a major concern as the growth of the thermally grown oxide (TGO) layer on the bondcoating creates stresses that greatly favour the thermal barrier spallation.
Monceau, Daniel, Oquab, Djar, Péré, Eve, Raffaitin, Aymeric, Vande Put, Aurélie   +4 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source

Interfacial toughness evaluation of thermal barrier coatings by bending test

Theoretical and Applied Mechanics Letters, 2018
: Determining the interfacial properties of thermal barrier coatings (TBCs) is imperative for their durability evaluation and further improvements. A ceramic coating (topcoat) and a NiCoCrALY bondcoat were atmospheric-plasma-sprayed (APS) on a stainless ...
Qi Zhu, Wei He, Lei Chen, Jianguo Zhu, Wenfeng Hao   +4 more
doaj   +1 more source

Thermal barrier coating materials

Materials Today, 2005
Improved thermal barrier coatings (TBCs) will enable future gas turbines to operate at higher gas temperatures. Considerable effort is being invested, therefore, in identifying new materials with even better performance than the current industry standard, yttria-stabilized zirconia (YSZ).
Materials Department, University of California, Santa Barbara CA 93106, USA ( host institution ), Clarke, David R. ( author ), Phillpot, Simon R. ( author )   +2 more
openaire   +2 more sources

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Impedance Study of Thermal Barrier Coating Deterioration in Gas Turbines [PDF]

Cailiao Baohu
Some inherent characteristics of thermal barrier coatings (TBC), such as porosity, thinner thickness and relatively high electrical resistivity, limit the application of traditional room temperature non-destructive testing techniques.Therefore, a method ...
DONG Xiaoke, ZHANG Hao, TAN Yu, CAI Yuhang, YUAN Weiming, LIANG Kexin, ZHANG Shenghan
doaj   +1 more source

Thermal and mechanical properties of APS-YbTa3O9 thermal barrier coatings

Nihon Kikai Gakkai ronbunshu, 2022
An advanced thermal barrier coating development is demanded for achieving the next generation gas turbine with a high efficiency. As one of many candidates in TBCs, RTa3O9 in a perovskite-type oxide attracts attention owing to the low thermal ...
Kazuma OKUNO, Masayuki ARAI, Kiyohiro ITO, Tatsuo SUIDZU, Yoichiro HABU   +4 more
doaj   +1 more source

Laser Powder Bed Fusion of Copper–Tungsten Composites for Heat Sink Applications in High‐Power Electronics

Advanced Engineering Materials, EarlyView.
This article demonstrates the successful qualification of a copper–tungsten composite for laser powder bed fusion. The resulting components exhibited high density, high thermal conductivity, and reduced thermal expansion. Heat sinks with complex geometries were successfully manufactured, clearly showcasing the material's potential for additive ...
Simon Rauh, Shashank Deepak Prabhu, Jannik Huber, Lioba Fischer, Gerhard Wolf, Nico Hempel, Peter Mayr   +6 more
wiley   +1 more source