Results 51 to 60 of about 1,410,120 (306)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Thermal performance enhancement of a heat exchanger using metal chain as a novel turbulator [PDF]

, 2021
Enhancing heat transfer in a heat exchanger system is critical to many industrial applications. There are many problems that require in-depth studies to find solutions.
Ghitheeth, Ali Hussein
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Monoacylglycerol acyltransferase maintains ionotropic receptor expression for cool temperature sensing and avoidance in Drosophila

Communications Biology
Sensory inputs of temperature dynamics in the environment are essential for appropriate physiological outputs. The responsiveness of sensory neurons is maintained by functional thermosensor expression.
Xiangmei Deng, Takuto Suito, Makoto Tominaga, Takaaki Sokabe   +3 more
doaj   +1 more source

From Chains to Chromophores: Tailored Thermal and Linear/Nonlinear Optical Features of Asymmetric Pyrimidine—Coumarin Systems

Molecules
Eleven novel asymmetric pyrimidine derivatives were synthesized. The pyrimidine core was functionalized with a coumarin chromophore and a pro-mesogenic fragment bearing either chiral or linear alkyl chains of variable length and substitution patterns ...
Prescillia Nicolas, Stephania Abdallah, Dong Chen, Giorgia Rizzi, Olivier Jeannin, Koen Clays, Nathalie Bellec, Belkis Bilgin-Eran, Huriye Akdas-Kiliç, Jean-Pierre Malval, Stijn Van Cleuvenbergen, Franck Camerel   +11 more
doaj   +1 more source

Thermal Behavior of Tunnel Segment Joints Exposed to Fire and Strengthening of Fire-damaged Joints with Concrete-filled Steel Tubes

Applied Sciences, 2019
Owing to its discontinuous configuration, segment joint is of particular concern when the shield tunnel lining is exposed to fire. The thermal behavior of such joints when exposed to fire was investigated experimentally in full scale.
Bo Wu, Yuechun Luo, Jianbo Zang
doaj   +1 more source

The spectral evolution of impulsive solar X-ray flares

, 2004
The time evolution of the spectral index and the non-thermal flux in 24 impulsive solar hard X-ray flares of GOES class M was studied in RHESSI observations. The high spectral resolution allows for a clean separation of thermal and non-thermal components
A. O. Benz, Benz, Brown, Brown, Cliver, Dennis, Fivian, Fletcher, Frost, Isobe, Kane, Kiplinger, Lin, Lin, Lu, P. C. Grigis, Parks, Saint-Hilaire, Smith   +18 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Phonons and Anisotropic Thermal Expansion Behaviour of NiX (X = S, Se, Te)

, 2019
Metal Chalcogenides have been known for important technological applications and have attracted continuous interest in their structure, electronic, thermal and transport properties.
Chaplot, S. L., Goel, Prabhatasree, Gupta, M. K., Mishra, S. K., Mittal, R., Sastry, P. U., Singh, Baltej, Thamizhavel, A.   +7 more
core   +1 more source

Numerical and experimental investigation of the thermal behavior and microstructure of wire arc additive manufactured 316L stainless steel straight wall part [PDF]

, 2022
Yongjiang Di, Zheng Zhao, Shikun Pang, J J Li   +3 more
openalex   +1 more source