Results 91 to 100 of about 972,673 (349)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Calculation of nanowire thermal conductivity using complete phonon dispersion relations

, 2003
The lattice thermal conductivity of crystalline Si nanowires is calculated. The calculation uses complete phonon dispersions, and does not require any externally imposed frequency cutoffs.
A. Balandin, C.W.J. Beenakker, D.H. Santamore, G. Mahan, J. Callaway, J. Zou, L.G.C. Rego, M. Asen-Palmer, M.G. Holland, M.J.M. de Jong, N. Mingo, W. Fon, Y.-J. Han, Yong-Jin Han   +13 more
core   +1 more source

METHOD OF THERMAL CALCULATION OF HEATING ROAD COVERING

, 2021
Ольга Василівна Володько, Н. В. Рогова   +1 more
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Lattice thermal conductivity of disordered NiPd and NiPt alloys

, 2006
Numerical calculations of lattice thermal conductivity are reported for the binary alloys NiPd and NiPt. The present work is a continuation of an earlier paper by us [PRB, 72, 214207 (2005)]which had developed a theoretical framework for the calculation ...
Abhijit Mookerjee, Aftab Alam, Bauer E, Brich F, Farrell T, Klemes P G, Parrot J E, Slack G A, Srivastava B N, Ziman M J   +9 more
core   +1 more source

THERMAL CALCULATION OF THE RECTIFIER

, 2022
A rectifier is an electrical device that converts alternating current (AC), which periodically changes direction, into direct current (DC), which flows in only one direction. Three-phase rectifiers make it possible to obtain large amounts of direct currents with low levels of output voltage ripples, which affects the reduction of requirements for the ...
openaire   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Calculation Method for Heat Transfer Coefficient of Urban Rail Transit Aluminum-alloy Vehicle Enclosure Structure Based on Thermal Resistance Model

Chengshi guidao jiaotong yanjiu
Objective According to the characteristics of urban rail transit aluminum-alloy vehicle enclosure structure，a K-value calculation method based on thermal resistance model is studied, thereby improving calculation accuracy and efficiency. Method The above
WANG Yunxiao, WANG Jing, TAN Wencai
doaj   +1 more source

Optimal cure cycle design for autoclave processing of thick composites laminates: A feasibility study [PDF]

The thermal analysis and the calculation of thermal sensitivity of a cure cycle in autoclave processing of thick composite laminates were studied. A finite element program for the thermal analysis and design derivatives calculation for temperature ...
Hou, Jean W.
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source