Results 51 to 60 of about 368,346 (339)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
, 2014 Citation: 'thermal conductivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.T06299 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
+4 more sources
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Cold Fronts and Gas Sloshing in Galaxy Clusters with Anisotropic Thermal Conduction
, 2012 (Abridged) Cold fronts in cluster cool cores should be erased on short timescales by thermal conduction, unless protected by magnetic fields that are "draped" parallel to the front surfaces, suppressing conduction perpendicular to the fronts.
Lee, D. +3 more
core +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Anisotropic Thermal Conduction and the Cooling Flow Problem in Galaxy Clusters
, 2009 We examine the long-standing cooling flow problem in galaxy clusters with 3D MHD simulations of isolated clusters including radiative cooling and anisotropic thermal conduction along magnetic field lines.
Balbus +26 more
core +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Analysis on thermal stress and heat conduction of functionally graded cylindrical shell
Journal of Aeronautical Materials, 2019 Ceramic-metal based functional graded materials (FGMs) are expected to be used in the design of airplane tail nozzle，not only because of their material characteristics varies with the changing of thickness continuously，but also because of the speed of ...
LIU Wenguang, FENG Xiayao, YAO Wan
doaj +1 more source
Heat conduction and energy diffusion in momentum-conserving 1D full lattice ding-a-ling model
, 2015 The ding-a-ling model is a kind of half lattice and half hard-point-gas (HPG) model. The original ding-a-ling model proposed by Casati {\it et.al} does not conserve total momentum and has been found to exhibit normal heat conduction behavior. Recently, a
Gao, Zhibin, Li, Baowen, Li, Nianbei
core +1 more source
Hot Accretion With Conduction: Spontaneous Thermal Outflows [PDF]
, 2006 Motivated by the low-collisionality of gas accreted onto black holes in Sgr A* and other nearby galactic nuclei, we study a family of 2D advective accretion solutions with thermal conduction.
Anderson M. +8 more
core +2 more sources