Results 51 to 60 of about 254,924 (310)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Thermal conductivity engineering of bulk and one-dimensional Si-Ge nanoarchitectures

Science and Technology of Advanced Materials, 2017
Various theoretical and experimental methods are utilized to investigate the thermal conductivity of nanostructured materials; this is a critical parameter to increase performance of thermoelectric devices.
Ali Kandemir, Ayberk Ozden, Tahir Cagin, Cem Sevik   +3 more
doaj   +1 more source

Experimental measurement of thermal conductivity of stereolithography photopolymer resins

SN Applied Sciences, 2022
The rise in the use of additive manufacturing highlights the importance of knowing the properties of the materials employed in this technology. Therefore, for the commercialization of thermal applications with this technology, heat management is ...
A. Oval-Trujillo, A. Rodríguez, G. Pérez-Artieda, Y. Dung, P. Alegría   +4 more
doaj   +1 more source

A further discussion on the effective thermal conductivity of metal foam: An improved model [PDF]

, 2015
In this study, we explain the causes and effects of the geometrical impossible result encountered in the widely adopted tetrakaidecahedron model (Boomsma and Poulikakos, 2001; Dai et al., 2010) for the effective thermal conductivities (ETCs) of metal ...
Jin, L.W., Yang, H., Gu, Z.L., Gu, Z. L., Zhao, M., Chai, J. C., Yang, Hui Yan, Chai, John, Jin, L. W.   +8 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Magnetically responsive multidimensional thermal display using liquid-metal-based flexible thermal switches [PDF]

APL Materials
Traditional thermal switches regulate thermal conductivity only in a single global direction, which limits their application in infrared thermal display.
Yuxia Dong, Xudong Zhang, Bingyang Cao
doaj   +1 more source

Effect of Cooling Rate and Modification by Strontium on the Thermal Conductivity of Al-8Si Alloy

Metals, 2021
Cooling rate plays a critical role in determining the thermal conductivity of Al-Si alloys. Although the effect of morphology and size of Si (changed by heat treatment) on its thermal conductivity has been investigated, the effect of cooling rates on ...
Guanyi Wang, Zhiping Guan, Jinguo Wang, Mingwen Ren, Ruifang Yan, Jiawang Song   +5 more
doaj   +1 more source

Development of thermal conductive consolidated activated carbon for adsorption refrigeration [PDF]

, 2012
A new type consolidated composite activated carbon (AC) was developed with a host matrix of expanded natural graphite treated with sulfuric acid (ENG-TSA).
Tamainot-Telto, Zacharie, Wang, L. W., Thorpe, Roger, Critoph, Robert E., Metcalf, Steven J.   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source