Results 221 to 230 of about 2,719,034 (384)

Accessing local structural disruption of Bid protein during thermal denaturation by absorption-mode ESR spectroscopy. [PDF]

RSC Adv, 2018
Hung CL, Lin YY, Chang HH, Chiang YW.
europepmc   +1 more source

Capillary Electrophoresis Can Detect the Simultaneous Presence of Hairpins and Self‐Dimers in Non‐Symmetric, Single‐Stranded DNA Oligomers

ELECTROPHORESIS, EarlyView.
ABSTRACT Free solution capillary electrophoresis (CE) has been used to show that non‐symmetric, single‐stranded DNA oligomers containing 26 nucleotides can exhibit peaks in the electropherograms that correspond to the simultaneous presence of self‐dimers and hairpins in the solution.
Earle Stellwagen, Nancy C. Stellwagen
wiley   +1 more source

Thermal denaturation profiles of proteome and blood serum of rats with drug-induced dementia. A DSC study: PS213. [PDF]

Porto Biomed J, 2017
Nizamova N, Abarova S, Traikov L, Koynova R, Tenchov B.   +4 more
europepmc   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

Exploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng, Ao Hua, Shiyou Li, Zhijie Zhang, Xiang Chen, Qiang Wang, Xing Wang, Zhiqin Chu, Xiangliang Yang, Zifu Li   +9 more
wiley   +1 more source

Multiscale NMR analysis of apple thermal denaturation

, 2018
Microstructure evolution of foods during cooking is difficult to assess because of the need of sensitive non destructive technique. To study such phenomena in apple, we undertook MRI, quantitative NMR and mechanical experiments at key temperatures of the cooking process (45, 50, 53, 60 and 70°C).
Clerjon, S., Leca, Alexandre, Renard, Catherine, Bonny, J.-M., Traore, Amidou   +4 more
openaire   +4 more sources

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Constrained thermal denaturation of DNA under fixed linking number

Open Physics, 2012
Bar Amir, Kabakçıoğlu Alkan, Mukamel David   +2 more
doaj   +1 more source

Self‐Emulsifying Biocatalysis Based on an Amphipathic Protein BslA‐Modified Esterase Functioning as a Fine‐Tuned System for Oil Hydrolysis

Food Bioengineering, EarlyView.
BslA is a promising tool to create an robust self‐emulsifying biocatalysis platform by reducing the droplet sizes of emulsion and improving its stability. It could guarantee the efficient hydrolysis of astaxanthin esters catalyzed by Est3‐14 without extra emusifier, increasing the yield of free astaxanthin to 184 μg·mL−1.
Xiaoxuan Yao, Kunpeng Gao, Hao Dong, Qian Sun, Jingyuan Liu, Yang Hu, Jianan Sun, Xiangzhao Mao   +7 more
wiley   +1 more source

Effects of protein and phosphate buffer concentrations on thermal denaturation of lysozyme analyzed by isoconversional method. [PDF]

Bioengineered, 2016
Cao XM, Tian Y, Wang ZY, Liu YW, Wang CX.   +4 more
europepmc   +1 more source

Atomic level description of the protecting effect of osmolytes against thermal denaturation of proteins [PDF]

, 2007
Stefano Pieraccini, Luigi Filippo Burgi, Alessandro Genoni, Anna Benedusi, Maurizio Sironi   +4 more
openalex   +1 more source