Results 61 to 70 of about 611,574 (314)

Fluidic and mechanical thermal control devices

open access: yes, 2021
In recent years, intensive studies on thermal control devices have been conducted for the thermal management of electronics and computers as well as for applications in energy conversion, chemistry, sensors, buildings, and outer space.
Andrej Kitanovski   +8 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Thermal comfort conditions in airport terminals: Indoor or transition spaces? [PDF]

open access: yes, 2016
This paper reports on the investigation of the thermal comfort conditions in three airport terminals in the UK. In the course of seasonal field surveys, the indoor environmental conditions were monitored in different terminal areas and questionnaire ...
Kotopouleas, Alkis   +1 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Thermal Actuation Based 3-DoF Non-Resonant Microgyroscope Using MetalMUMPs [PDF]

open access: yes, 2009
High force, large displacement and low voltage consumption are a primary concern for microgyroscopes. The chevron-shaped thermal actuators are unique in terms of high force generation combined with the large displacements at a low operating voltage in ...
Lai, YJ   +18 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Thermal performance enhancement in a circular tube with louvered V-winglet inserts: effect of louver angle and opening area

open access: yesCase Studies in Thermal Engineering
This paper presents an evaluation of the thermal performance of a circular tube with louvered V-winglet inserts (LVWs) under turbulent flow conditions.
Anuwat Saenpong   +3 more
doaj   +1 more source

Reliability evaluation and thermal design of medium-voltage converter for underwater long-distance high-voltage direct current transmission system

open access: yesThe Journal of Engineering, 2019
Underwater long-distance high-voltage direct current transmission system can provide long-term, reliable, and sustainable energy for ocean observatories system which has higher reliability requirement than onshore or conventional underwater equipment. As
Siyuan Ma   +10 more
doaj   +1 more source

Experimental and numerical investigation of an air-to-water heat pipe-based heat exchanger [PDF]

open access: yes, 2015
An experimental and analytical investigation was conducted on an air-to-water heat exchanger equipped with six wickless heat pipes (thermosyphons) charged with water as the working fluid.
Mroue, H   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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