Results 51 to 60 of about 11,334,328 (240)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Numerical Simulation of Lateral Ventilation for Moisture Retention of Grain Storage at Different Ventilation Temperatures

open access: yesLiang you shipin ke-ji, 2021
In order to ensure the quality of rice in long-term storage, it is of great significance to simulate and analyze the horizontal cooling and water-retaining ventilation under the conditions of same humidity and different ventilation temperatures.Based on ...
WANG Ke   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

An Overview of Modern Thermo-Conductive Materials for Heat Extraction in Electrical Machines

open access: yesIEEE Access, 2020
This article presents a comprehensive review of the modern thermo-conductive materials that have potential to improve the heat extraction in electrical machines by conduction.
Mehmet Caglar Kulan   +2 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Energy, economic, and environmental analysis of a waste-to-energy-to-zero system

open access: yesCleaner Chemical Engineering
This study presents a new waste-to-energy-to-zero management under the energy, economic, and environmental implications. The survey data implies a total municipal solid waste (MSW) generation of 17.85 Ton/d.
Sakkarat Khwamman, Nattaporn Chaiyat
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Reliability evaluation and thermal design of medium-voltage converter for underwater long-distance high-voltage direct current transmission system

open access: yesThe Journal of Engineering, 2019
Underwater long-distance high-voltage direct current transmission system can provide long-term, reliable, and sustainable energy for ocean observatories system which has higher reliability requirement than onshore or conventional underwater equipment. As
Siyuan Ma   +10 more
doaj   +1 more source

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