Results 31 to 40 of about 175,829 (264)

Coupled Transport Effects in Solid Oxide Fuel Cell Modeling

Entropy, 2022
With its outstanding performance characteristics, the SOFC represents a promising technology for integration into the current energy supply system. For cell development and optimization, a reliable quantitative description of the transport mechanisms and
Aydan Gedik, Nico Lubos, Stephan Kabelac
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

THERMAL DIFFUSION AS A PURIFICATION TOOL [PDF]

Annals of the New York Academy of Sciences, 1966
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/72201/1/j.1749-6632.1966.tb49745.x ...
Prabhudesai, R. K., Powers, J. E.
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Tridimensional multiphysics model for the study of photo-induced thermal effects in arbitrary nano-structures [PDF]

Journal of the European Optical Society-Rapid Publications, 2011
In the present paper, we detail the implementation of a numerical scheme based on the Finite Element Method (FEM) dedicated to a tri-dimensional investigation of photo-induced thermal effects in arbitrary nano-structures. The distribution of Joule losses
Demésy Guillaume, Gallais Laurent, Commandré Mireille   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Coupled model for contaminant diffusion, osmosis and consolidation in soil considering thermal effects

Yantu gongcheng xuebao, 2022
To explore the influences of temperature on pollutant transport, a coupled model for contaminant diffusion in soils, osmosis and consolidation considering the thermal effects is proposed to reflect the dynamic changes of physical properties of soils and ...
TIAN Gai-lei , ZHANG Zhi-hong
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Simulation of composition changes in reservoirs with large hydrocarbon columns and temperature gradient

Georesursy, 2018
This paper compares three methods for calculation of initial composition variation with depth in hydrocarbon reservoirs: considering thermal diffusion, considering temperature gradient without thermal diffusion effects; and by gravity forces only. Newton
A.V. Yashin, I.M. Indrupskiy, O.A. Lobanova   +2 more
doaj   +1 more source