Results 41 to 50 of about 19,893 (259)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

THERMAL DIFFUSIVITY MEASUREMENT OF SOLID USING PYROELECTRIC SENSOR

ASEAN Journal on Science and Technology for Development, 2017
The recently developed pyroelectric spectroscopic technique has been used to measure the thermal diffusivity of solids. The method has been applied to conductors and insulator where by the thermal wave is measured at various lateral distances on the ...
B. Z. Azmi, Y. T. Ling, M. Hashim, W. M. M. Yunus, M. M. Moksin   +4 more
doaj   +1 more source

Low-frequency heat waves transport in graded Si–Ge alloys

AIP Advances, 2023
In this work, we consider a rigid heat conductor graded material subjected to an oscillating thermal signal applied on its boundary. We use a recently proposed novel concept, the so-called spectral diffusivity, to characterize the response of the ...
Iván Rivera, Raúl Salgado-García, Federico Vázquez   +2 more
doaj   +1 more source

THERMAL DIFFUSION AS A PURIFICATION TOOL [PDF]

Annals of the New York Academy of Sciences, 1966
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/72201/1/j.1749-6632.1966.tb49745.x ...
Prabhudesai, R. K., Powers, J. E.
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Determining the In Situ Apparent Thermal Diffusivity of a Sandy Soil

Revista Brasileira de Ciência do Solo, 2018
: The thermal wave amplitude method is used to determine soil thermal diffusivity in situ for a sandy soil in Mexico (Coatzacoalcos, Veracruz). Soil diurnal temperature fluctuations were measured from depths of 0.05 to 0.65 m, in 0.01 m increments ...
Oscar Fernando Silva Aguilar, Jorge Alberto Andaverde Arredondo, Beatris Adriana Escobedo Trujillo, Artemio Jesús Benitez Fundora   +3 more
doaj   +1 more source

Thermal diffusivity of sintered 12CaO-7Al2O3 [PDF]

Science of Sintering, 2003
The thermal diffusivity and some electrical transport properties of sintered 12CaO-7Al2O3 were determined using a photoacoustic method with a transmission detection configuration.
Nikolić Pantelija M., Luković D., Savić S., Urošević Dragan B., Đurić S.   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Estimation of Thermal Diffusivity in the Inverse Heat Transfer Problem for a Polymer Plate

Modelling
This study investigates the inverse estimation of the effective thermal diffusivity of a polytetrafluoroethylene (PTFE) plate subjected to oscillatory heating from a hot plate with on–off control.
Douglas M. Rieger, Alisson L. Daga, Ervin K. Lenzi, Marcelo K. Lenzi   +3 more
doaj   +1 more source