Results 81 to 90 of about 905,279 (309)

Test bench for radiative waste heat recovery in steel mills

Publisher Copyright: © 2025This paper presents the design, manufacturing, and validation of a test bench for a radiation waste heat recovery system, which can reproduce the operating conditions of a real steelmaking factory, in particular, continuous ...
Arroiabe, P. F., López, S., Mesonero, I., Arteche, M. Gómez de, Iturralde, J., Martinez-Agirre, M., Herrero, S., Bou-Ali, M. Mounir   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Pile heat exchangers: thermal behaviour and interactions [PDF]

, 2013
Thermal piles – that is structural foundation piles also used as heat exchangers as part of a ground energy system – are increasingly being adopted for their contribution to more sustainable energy strategies for new buildings.
Loveridge, F.A., Powrie, W., Powrie, W, Loveridge, F   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Study on the Thermal Effects and Characteristics of Free Radical Evolution in Coal Oxidation at Different Moisture Content

Fire
To investigate the influence of moisture on the exothermic properties of coal oxidation, this study investigated the variation in thermal effect and radical parameters in the oxidation process of coal under different moisture content.
Yanni Zhang, Fangyan Zhai, Di Yao, Jun Deng, Pan Shu, Zhengxiao Duan   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Thermal angular Doppler effect , polarized thermal waves and thermal rotational superradiance

, 2023
We discuss at first the old question, studied originally by Planck and Einstein, whether thermodynamic equilibrium could be described by a covariant law or if it was an invariant property in every reference frame.
bei gianpaolo
core  

Optothermotronic effect as an ultrasensitive thermal sensing technology for solid-state electronics [PDF]

, 2020
The thermal excitation, regulation, and detection of charge carriers in solid-state electronics have attracted great attention toward high-performance sensing applications but still face major challenges.
Dao, DV, Dinh, T., Nguyen, N-T, Nguyen, T-K, Nguyen, T, Dinh, T, Nguyen, T., Foisal, A. R. M., Foisal, ARM, Phan, H-P, Nguyen, T.-K., Phan, H.-P., Dao, D. V., Nguyen, N.-T.   +13 more
core   +1 more source