Results 71 to 80 of about 38,941 (210)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Decoupling Analysis of Ignition Processes of Ammonia/N-Heptane Mixtures

Energies
To further understand the influence of n-heptane on the ignition process of ammonia, an isotope labeling method was applied in the current investigation to decouple the influence of the chemical effect, the thermal effect, and the effect of O radical ...
Zheng Li, Yilin Zhang, Jingrui Li, Changchun Xu, Huabing Wen, Jianhua Shen, Haiguo Jing, Haifeng Liu, Xinyan Wang, Hua Zhao   +9 more
doaj   +1 more source

Effect of Sintering on Thermal Conductivity and Thermal Barrier Effects of Thermal Barrier Coatings

Chinese Journal of Aeronautics, 2012
AbstractThermal barrier coatings (TBCs) are mostly applied to hot components of advanced turbine engines to insulate the components from hot gas. The effect of sintering on thermal conductivity and thermal barrier effects of conventional plasma sprayed and nanostructured yttria stabilized zirconia (YSZ) thermal barrier coatings (TBCs) are investigated.
WANG, Kai, PENG, Hui, GUO, Hongbo, GONG, Shengkai   +3 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Numerical simulation of heat effect and strain effect on gas drainage

Meikuang Anquan
In order to explore the influence of thermal effect and strain on gas drainage, a fluid solid thermal coupling model considering coal deformation, gas adsorption and thermal effect was established to simulate the influence of thermal effect and strain on
Linfeng ZHANG, Yanguo YANG, Nan FAN, Kang LIU, Wenjun YAO   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Thermal effect caused by low-temperature oxidation of heavy crude oil under quasi-adiabatic condition

Youqicang pingjia yu kaifa, 2020
The influences of temperature, quartz sand, detritus and specific surface area of medium on thermal release caused by low-temperature oxidation of heavy crude oil of Jiqi Oilfield have been investigated by self-designed high-temperature and high-pressure
PAN Jingjun, PU Wanfen, ZHAO Shuai, KANNI Zhati, WANG Ruyan, Li Yibo, WAN Zheng, GU Fei   +7 more
doaj  

A Numerical Study on Influence of Temperature on Lubricant Film Characteristics of the Piston/Cylinder Interface in Axial Piston Pumps

Energies, 2018
The loss of kinetic energy of moving parts due to viscous friction of lubricant causes the reduction of piston pump efficiency. The viscosity of lubricant film is mainly affected by the thermal effect. In order to improve energy efficiency of piston pump,
Yueheng Song, Jiming Ma, Shengkui Zeng
doaj   +1 more source