Results 31 to 40 of about 6,138,248 (244)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Thermal stresses in pipes [PDF]
, 2002 This study presents results about thermal stresses in externally heated pipes that are subjected to different flow types: laminar flow, turbulent flow, and pulsating flow. The effect o f flow Reynolds number on thermal stresses in the pipe is studied. To
Al-Zaharnah, Iyad
core +2 more sources
Performance analysis of non-circular microchannels flooded with CuO-water nanofluid [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Gupta, KD +3 more
core +5 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Journal of Engineering, 2011 Experiments have been conducted to study the local and average heat transfer by mixed convection for hydrodynamically fully developed, thermally developing and fully developed laminar upward air flow in an inclined annulus with adiabatic inner cast iron
Akeel A. Mohammed
doaj +1 more source
Heat Transfer to Liquid Metals in a Thermal Entrance Region [PDF]
, 1952 The purpose of the present work is to explore analytically and experimentally the heat transfer to liquid metals in turbulent flow within the thermal entrance region of circular tubes having uniform wall temperature. Since liquid metals are characterized
Harrison, William B.
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
International Journal of Rotating Machinery, 2005 Internal cooling is one of the effective techniques to cool turbine blades from inside. This internal cooling is achieved by pumping a relatively cold fluid through the internal-cooling channels.
R. Ben-Mansour, L. Al-Hadhrami
doaj +2 more sources
The Gravothermal Instability at All Scales: From Turnaround Radius to Supernovae
Universe, 2019 The gravitational instability, responsible for the formation of the structure of the Universe, occurs below energy thresholds and above spatial scales of a self-gravitating expanding region, when thermal energy can no longer counterbalance self-gravity ...
Zacharias Roupas
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source