Results 31 to 40 of about 151,392 (262)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
By combining the thermal elastohydrodynamic lubrication theory, thermoelastic mechanics theory and principle of heat-pressure conversion, a method was presented to solve the material thermal expansion coefficient of solid surface in the thermal ...
LU ZunYou
doaj
The Anisotropic Thermal Expansion of Non-linear Optical Crystal BaAlBO3F2 Below Room Temperature
Thermal expansion is a crucial factor for the performance of laser devices, since the induced thermal stress by laser irradiation would strongly affect the optical beam quality.
Xingxing Jiang +12 more
doaj +1 more source
In order to explore the influence of coal deformation caused by temperature and desorption on seepage characteristics in the process of heat injection mining of coalbed methane, the permeability test, thermal expansion, and constant temperature ...
Xiaoyu Su +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Contribution of thermal expansion and
A theoretical model is developed to describe the experimental results obtained for the isobaric thermal conductivity of rare gas solids (RGS). The isobaric thermal conductivity of RGS has been analysed within Debye approximation with regard to the effect
O.I.Pursky, V.A.Konstantinov
doaj +1 more source
Thermal Deformation of Granite under Different Temperature and Pressure Pathways
The thermal cracking of rocks is the phenomenon of expansion and deformation of mineral particles inside the rocks. The thermal deformation of the same granite sample under different heating pathways was meticulously analyzed, and the effect of the ...
Peng Zhao, Zi-jun Feng
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Thermal Expansion of Alkaline-Earth Borates
The thermal expansion of four alkaline-earth borates, namely Ca3B2O6 (0D), CaB2O4 (1D), Sr3B14O24 (2D) and CaB4O7 (3D), has been studied by in situ high-temperature powder X-ray diffraction (HTXRD).
Rimma Bubnova +4 more
doaj +1 more source

