Results 51 to 60 of about 160,836 (309)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Effects of Y content on microstructures and thermal expansion behavior of Mg-Al-Y alloys
Materials Research Express, 2021 Low thermal expansion alloys play an important role in the applications of high-precision instruments because of their excellent dimensional stability under thermal shock. Hence, the effect of Y content on coefficient of thermal expansion (CTE) of Mg-1Al-
Hongbin Ma, Zhuohua Li, Jinhui Wang
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
IRREVERSIBLE THERMAL EXPANSION OF REPLICATED ALUMINIUM FOAM
Acta Metallurgica Slovaca, 2018 Irreversible thermal expansion of large items made of the replicated aluminium foam was detected during the extraction of soluble filler from Al-NaCl composite. Sources of the phenomenon were investigated The expansion discovered was caused by incomplete
Arkady Finkelstein, Dmitry Husnullin
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Thermal expansion coefficient of few-layer MoS2 studied by temperature-dependent Raman spectroscopy
Scientific Reports, 2021 The thermal expansion coefficient is an important thermal parameter that influences the performance of nanodevices based on two-dimensional materials. To obtain the thermal expansion coefficient of few-layer MoS2, suspended MoS2 and supported MoS2 were ...
Zhongtao Lin +5 more
doaj +1 more source
Understanding the role of guest ions in the control of thermal expansion of FeFe(CN)6
Results in Physics, 2022 Understanding the role of guest species in framework materials is important to successfully achieve the control of thermal expansion. In this work, the thermal expansion of the Prussian blue analogue FeFe(CN)6 has been effectively tailored from negative,
Qilong Gao +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Contribution of thermal expansion and
Condensed Matter Physics, 2007 A theoretical model is developed to describe the experimental results obtained for the isobaric thermal conductivity of rare gas solids (RGS). The isobaric thermal conductivity of RGS has been analysed within Debye approximation with regard to the effect
O.I.Pursky, V.A.Konstantinov
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source