Results 221 to 230 of about 2,110,972 (292)

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

open access: yesAdvanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu   +11 more
wiley   +1 more source

Small-scale phreatic explosions from a low-enthalpy hydrothermal system caused the abandonment of Milos Island (Greece) in Roman times. [PDF]

open access: yesSci Rep
Sulpizio R   +11 more
europepmc   +1 more source

Multifunctional Vertical Bulk‐Heterojunction Transistors With Amorphous GaOx for Neuromorphic Perception‐to‐Decision

open access: yesAdvanced Science, EarlyView.
A multifunctional vertical bulk‐heterojunction transistor (MVBT) with amorphous GaOx integrates four functionalities within a single neuromorphic device. Gate‐source operation enables 254 nm deep‐ultraviolet sensing and threshold neuronal firing, whereas three‐terminal operation supports broadband UV–vis‐NIR synaptic functions and bias‐controlled ...
Jinkui Si   +12 more
wiley   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

A Water Compartment Cell Culture Lid Enables Stable Longitudinal Recording of Neuronal Networks In Vitro

open access: yesAdvanced Science, EarlyView.
A cell culture lid with an integrated water compartment eliminates evaporation from microelectrode arrays while preserving gas exchange. Freed from the osmotic drift and repeated medium exchanges that disturb conventional recordings, patterned human iPSC‐derived neuronal networks are recorded continuously for five weeks. Single‐spike resolution reveals
Benedikt Maurer   +4 more
wiley   +1 more source

Optimizing Wheat Milling By-Products: An Overview of Processing Techniques. [PDF]

open access: yesFoods
Khashaba RA   +6 more
europepmc   +1 more source

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