Results 71 to 80 of about 20,614 (298)

Detection of hidden defects of thermal protection of buildings and determination of some thermal properties of structural building materials by Non-destructive Thermal Imaging method

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2023
Objective. The purpose of the work is the practical approbation of a nondestructive thermal imaging method to identify hidden (invisible) defects and qualitative analysis of the thermal protection of a complex of construction objects in the city of ...
D. F. Karpov, M. V. Pavlov, A. G. Gudkov
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

The Influence of Supply Channel Design on the Gas-Dynamic Structure of Air Flow in a Vertical Conical Diffuser

open access: yesApplied Sciences, 2023
Vertical conical diffusers are used in power engineering, chemical industry, technological processes, and other industries. The efficiency of many machines and pieces of equipment is determined by the gas-dynamic and heat-exchange perfection of processes
Leonid Plotnikov, Alexander Ryzhkov
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Low-cost thermal imager for plant phenotyping. [PDF]

open access: yes, 2017
This work uses a Flir Lepton 3 longwave infrared imager integrated with a Raspberry Pi computer to produce thermal images of crops. The longwave infrared sensor can detect the thermal radiation emitted by objects near room temperature and then determine ...
SOUZA, M. A. A. de   +3 more
core  

ANALISIS EMISIVITAS KLEM SAMBUNG TRANSMISSION LINE BAY 150 KV MENGGUNAKAN THERMAL IMAGER [PDF]

open access: yes, 2021
Hot spot at a substation equipment connection point of the State Electricity Company (PLN), is one of the parameters that are monitored and analyzed changes at all times.
WK, Diah Arie   +2 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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