Results 71 to 80 of about 838,817 (317)

Production of Resonances in a Thermal Model [PDF]

Acta Physica Hungarica A) Heavy Ion Physics, 2005
We discuss the pi+ pi- invariant-mass correlations and the resonance production in a thermal model with single freeze-out. The predictions are confronted with the data from the STAR Collaboration.
Broniowski, Wojciech, Florkowski, Wojciech, Hiller, Brigitte   +2 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Simulation of Magnetic Component Models in Electric Circuits including Dynamic Thermal Effects

, 2002
It is essential in the simulation of power electronics applications to model magnetic components accurately. In addition to modeling the nonlinear hysteresis behaviour, eddy currents and winding losses must be included to provide a realistic model.
Ross, J. Neil, Brown, Andrew D., Wilson, Peter R., J.N. Ross, P.R. Wilson, A.D. Brown   +5 more
core   +1 more source

Evolution and Modern Approaches for Thermal Analysis of Electrical Machines [PDF]

, 2009
In this paper, the authors present an extended survey on the evolution and the modern approaches in the thermal analysis of electrical machines. The improvements and the new techniques proposed in the last decade are analyzed in depth and compared in ...
Shanel, M., D. STATON, M. SHANEL, Aldo Boglietti, Andrea Cavagnino, C. MEJUTO, Carlos Mejuto, David Staton, M. MUELLER, Mueller, M., Staton, D., Mejuto, C., Martin Shanel, Boglietti, Aldo, Cavagnino, Andrea, Markus Mueller   +15 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

DEVELOPMENT OF AN ACCURATE THERMAL MODEL TO BE USED FOR THE EVALUATION OF POWER BIPOLAR TRANSISTOR JUNCTION TEMPERATURE IN AUTOMOTIVE APPLICATION

, 2023
reservedThe objective of this thesis is to perform electrical and thermal measurements of a DPAK Silicon Power Bipolar Transistor for Automotive application, aiming to characterize a thermal model to be used in 3D CATIA-FLoEFD software.
GOBBI, DAVIDE
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Mathematical Modeling of Thermal Ablation

Critical Reviews™ in Biomedical Engineering, 2010
Ablation techniques have become a widespread choice for the treatment of cancerous tumors for which surgical resection techniques have a poor prognosis. The minimally invasive nature and high success rate when performed by experienced clinicians mean that ablation is likely to remain a core technique. However, the success rate can drop off dramatically
Payne, S, Peng, T, O'Neill, D
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source