Results 71 to 80 of about 2,147 (164)

Genomic Structural Equation Modeling Provides an Initial View of the Genetic Architecture Related to Type 1 Gaucher Disease

Human Mutation, Volume 2026, Issue 1, 2026.
The genetic architecture underlying traits associated with Type 1 Gaucher disease (GD1) remains insufficiently explored. We integrated genomic structural equation modeling and multiple post–genome‐wide association study (GWAS) methodologies to prioritize candidate SNPs associated with GD1‐related variation, identifying 15 loci with strong statistical ...
Shijie Ren, Mingmin Du, Jingyuan Liu, Boyu Li, Jianping Liu, Xiaomeng Lang, Shaoqiu Chen   +6 more
wiley   +1 more source

Drill-bit upper limit temperature calculation when drilling bones in orthopedic surgery

Biotechnology & Biotechnological Equipment
The orthopedic manipulation of bone drilling is performed during the osteosynthesis of bone fractures. It is characterized by a set of input and output parameters.
Tony Boiadjiev, George Boiadjiev, Ivan Chavdarov, Kamen Delchev, Rumen Kastelov   +4 more
doaj   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

Small Science, Volume 5, Issue 12, December 2025.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li, Xudong Xie, Chong Ding, Shengming Zhang, Liangcong Hu, Bobin Mi, Mengfei Liu, Guohui Liu   +7 more
wiley   +1 more source

Optimization of drill bit geometries for minimum thermal damage in bone drilling [PDF]

Thermal injury is a common post-operative effect in bone drilling surgeries. The extreme heat generated during the drilling process kills bone cells, which causes irreversible bone death.
Mohamad Faris, Mohd Ashri, Ahmad Razlan, Yusoff, Razhan, Hassan, Rodianah, Alias, Fatin, Alias, Shahrizan, Jamaludin, Muhammad, Rizwan, Mohd Faizal, Ali Akhbar   +7 more
core   +1 more source

Lasertherapy in the optimization of the treatment of osteomyelitis and osteonecrosis of the jaws

, 2023
Osteomyelitis is a progressive inflammatory process in bone tissue and can be acute, subacute or chronic; it begins in the bone marrow, spreads and extends to the neighboring soft tissues through the bone, involving the medullary, cortical, spongy and
Thalita Andrade Santos
core  

Bone Drilling in Orthopedic Surgery: A Systematic Review of Thermal Osteonecrosis, Process Parameters, and Cooling Strategies

This systematic review investigates how bone drilling parameters and cooling strategies influence heat generation and the risk of thermal osteonecrosis in orthopedic surgery. Excessive temperatures during drilling can damage bone tissue, compromise the bone–implant interface, and increase the risk of loosening, non-union, and implant failure.
Kovacs, Elena, Dominguez, Rafael, Belkacem, Sara   +2 more
openaire   +3 more sources

Thermographic analysis of perforations in polyurethane blocks performed with experimental conical drill bit in comparison to conventional orthopedic drill bit: a preliminary study

BMC Research Notes
Objective Conical orthopedic drill bits may have the potential to improve the stabilization of orthopedic screws. During perforations, heat energy is released, and elevated temperatures could be related to thermal osteonecrosis.
Inácio Bernhardt Rovaris, Anderson Luiz de Carvalho, Gabriel Aardewijn Silva, Daniel Guimarães Gerardi, Marcelo Meller Alievi   +4 more
doaj   +1 more source

DEVELOPMENT OF IN-SITU TEMPERATURE PREDICTION MODELS FROM CADAVERIC HUMAN FEMUR FOR BONE DRILLING

, 2018
Thermal osteonecrosis of bone in drilling procedure is caused by improper parameters which can lead to poor bone-implant integration and loss of fixation.
PONNUSAMY PANDITHEVAN, NATARAJAN VINAYAGA MURUGA PANDY, CHINNUSAMY PALANIVEL   +2 more
core   +1 more source

Optimisation of plasma sprayed hydroxyapatite coatings [PDF]

, 2008
Hydroxyapatite, (HA), is a calcium phosphate bioceramic material which has an almost identical chemical composition to that of the mineral component of bone.
Levingstone, Tanya J.
core  

Thermal analysis of a dry cooling method in a dental implant drilling procedure: an in vitro randomized study

BMC Oral Health
Background Excessive temperature rise during drilling can lead to thermal bone damage and compromise implant success. This in vitro study aimed to evaluate the effectiveness of the newly introduced “dry cooling” method to control heat generation during ...
Kubilay Baris, Meltem Hendek, Hatice Ebru Olgun   +2 more
doaj   +1 more source