Results 41 to 50 of about 7,953,798 (287)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Effects of element addition on the microstructure and thermophysical properties of seven-principal cations rare-earth high-entropy oxide

open access: yesJournal of Materials Research and Technology
Three new rare-earth high-entropy oxides with compositions of (Y1/7La1/7Nd1/7Sm1/7Gd1/7Yb1/7Lu1/7)2O3 (7HEO), (Y1/8La1/8Nd1/8Sm1/8Gd1/8Yb1/8Lu1/8Ce1/8)2O3 (8HEO) and (Y1/10La1/10Nd1/10Sm1/10Gd1/10Yb1/10Lu1/10Ce1/10Zr1/10Hf1/10)2O3 (10HEO) were prepared ...
Xinyu Ping   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Development of structure and properties during thermal calendering of polylactic acid (PLA) fiber webs

open access: yeseXPRESS Polymer Letters, 2008
Due to its thermoplastic and biodegradable nature, poly(lactic acid) (PLA) holds good promise in its increasing use in the form of fibers for medical, agricultural, apparel, upholstery, hygiene, and other applications.
doaj   +1 more source

Effect of Sr2TiMnO6 fillers on mechanical, dielectric and thermal behaviour of PMMA polymer [PDF]

open access: yesJournal of Advanced Dielectrics, 2015
Composites of poly(methyl methacrylate) (PMMA) and Sr2TiMnO6 (STMO) were fabricated via melt mixing followed by hot pressing technique. These were characterized using X-ray diffraction (XRD), thermo gravimetric analysis (TGA), differential scanning ...
P. Thomas   +3 more
doaj   +1 more source

Influence of Temperature on the Thermal Properties of the Core Material - the Coefficient of Temperature Conductivity, Specific Heat Capacity, Thermal Conductivity

open access: yesInternational Journal of Technology, 2023
The absorption of heat by rocks is accompanied by an increase in the kinetic energy of molecules and atoms and is recorded by a change in rock temperature. The thermal properties of rocks characterize the ability to transfer and absorb heat and change
Efim Burlutsky   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Study on properties of composites reinforced by heat treated glass fibres simulating thermal recycling conditions [PDF]

open access: yes, 2013
In the present study, commercial chopped glass fibres were heat treated at 300°C, 450°C, 500°C and 600°C to imitate a composite thermal recycling process.
Thomason, James   +2 more
core   +2 more sources

Experimental study on the effect of basalt fiber reinforced expanded polystyrene foams on the compressive strength of lightweight concrete

open access: yesAIP Advances
Reducing the structural load and operational energy consumption of buildings is a trend in the development of the construction industry, and lightweight concrete has become a research hotspot because of its dual characteristics of low density and high ...
Zheng Cao   +10 more
doaj   +1 more source

Partially bio-based and tough polyesters, poly(ethylene 2,5-thiophenedicarboxylate-co-1,4-cyclohexanedimethylene 2,5-thiophenedicarboxylate)s

open access: yeseXPRESS Polymer Letters, 2019
Novel tough bio-based polyesters poly(ethylene 2,5-thiophenedicarboxylate-co-1,4-cyclohexanedimethylene 2,5-thiophenedicarboxylate)s (PECTFs) were synthesized from 2,5-thiophenedicarboxylic acid (TDCA), 1,4-cyclohexanedimethanol (CHDM) and ethylene ...
G. Q. Wang   +6 more
doaj   +1 more source

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