Results 71 to 80 of about 32,150 (294)

The intensive summation of thermal sensations. [PDF]

Psychological Monographs, 1921
n ...
Baron, Annette, Bentley, Madison
openaire   +1 more source

TRPV1‐lineage neurons are required for thermal sensation [PDF]

The EMBO Journal, 2010
The ion-channel TRPV1 is believed to be a major sensor of noxious heat, but surprisingly animals lacking TRPV1 still display marked responses to elevated temperature. In this study, we explored the role of TRPV1-expressing neurons in somatosensation by generating mice wherein this lineage of cells was selectively labelled or ablated. Our data show that
Santosh K, Mishra, Sarah M, Tisel, Peihan, Orestes, Sonia K, Bhangoo, Mark A, Hoon   +4 more
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

The use of a thermophysiological model in the built environment to predict thermal sensation : coupling with the indoor environment and thermal sensation

, 2013
Thermal comfort, influenced by thermal sensation is an important building performance indicator. In this study we discuss the use of a thermophysiological model in the built environment to assess thermal sensation. In the context of this work, the use of
Loomans, M.G.L.C., Kingma, BRM Boris, Kingma, B.R.M., Marken Lichtenbelt, van, W.D., Marken Lichtenbelt, W Wouter van, Loomans, MGLC Marcel, Wit, de, M.H., Frijns, A.J.H.; id_orcid, Schellen, L Lisje, Wit, MH Martin de, Frijns, AJH Arjan, Schellen, L., Frijns, A.J.H.   +12 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Determination of thermal sensation on transient conditions [PDF]

, 2015
The objective of this study is to investigate the difference in thermal environment and human response between air-conditioned closed space and a semi-open space. The thermal response of the subjects in transitional space as they experienced step changes
Gital, Yakubu Y., Hussein, Mohd Kher, Dahlan, Nur Dalilah   +2 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Experimental study on overall and local thermal comfort under different radiation intensities [PDF]

E3S Web of Conferences
Shortwave radiation constitutes the principal source of thermal loading within automobile cabins, exhibiting characteristics of transient change and non-uniform distribution.
Zeng Yingqi, Zhou Xiang, Zhai Yongchao, Xia Haifeng   +3 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Models and Indicators to Assess Thermal Sensation Under Steady-state and Transient Conditions

Energies, 2019
The assessment of thermal sensation is the first stage of many studies aimed at addressing thermal comfort and at establishing the related criteria used in indoor and outdoor environments. The study of thermal sensation requires suitable modelling of the
Diana Enescu
doaj   +1 more source