Results 51 to 60 of about 6,436,584 (378)

Protein engineering of CMP kinases to improve thermal stability and resultant production of 3′-sialyllactose

Biotechnology & Biotechnological Equipment, 2022
Protein engineering is an effective method to improve the thermal stability of biological macromolecules. Cytidine monophosphate kinase (CMK) is a key enzyme involved in nucleotide metabolism and participates in the production of cytidine triphosphate ...
Jingjing Wang, Jinyong Wu, Zhongkui Li, Xiangsong Chen, Weiwei Liu, Jianming Yao   +5 more
doaj   +1 more source

NASA space materials research [PDF]

, 1985
The effect of the space environment on: (1) thermal control coatings and thin polymer films; (2) radiation stability of 250 F and 350 F cured graphite/epoxy composites; and (3) the thermal mechanical stability of graphite/epoxy, graphite/glass composites
Sykes, G. F., Tenney, D. R., Tompkins, S. S.   +2 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Thermal Degradation of Blends of Polystyrene and poly(sodium 4-styrenesulfonate) and the copolymer, poly(styrene-co-sodium 4-styrenesulfonate) [PDF]

, 1999
The thermal degradation of blends and copolymers of styrene with styrenesulfonic acid has been studied using thermogravimetric analysis, TGA/FTIR, and cone calorimetry.
Wilkie, Charles, Yao, Qiang
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

An exploration of enhancing thermal stability of leather by hydrophilicity regulation: effect of hydrophilicity of phenolic syntan

Journal of Leather Science and Engineering, 2022
Effect of retanning on the thermal stability of leather is eliciting increasing attention. However, the relationship between the hydrophilicity of retanning agents and the heat resistance of leather and the corresponding mechanism remain unclear. Herein,
Qingyong Sun, Yunhang Zeng, Yue Yu, Ya-nan Wang, Bi Shi   +4 more
doaj   +1 more source

Thermal Stability of Mg/TeO2 Priming Compositions

Medžiagotyra, 2021
The insensitive ignitors with magnesium/tellurium dioxide (Mg/TeO2) priming composition installed on the spacecraft will experience a harsh thermal environment. Therefore, it is necessary to verify their availability at extreme temperatures. Differential
Xiang-run ZHAO, Nan YAN, Wu-si DAI, Yao-kun YE, Shi-xin JIN, Jin-hong HUANG   +5 more
doaj   +1 more source

Thermal stability of Hg1-xMnxTe compound semiconductors [PDF]

, 1992
The thermal behaviour of Hg1-xMnxTe single crystals is investigated by means of the RBS/channeling technique. The stoichiometry parameter x ranges from 0.08 to 0.2.
Brandt, Chu, Feldman, Furdyna, Furdyna, Gałazka, Mikulko, Opyd, Piotrowski, Reine, Takita, Wall   +11 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source