Results 71 to 80 of about 4,303,033 (308)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Stability in Multi-Position Controlled Thermal Processes

Measurement + Control, 1969
The common distributed parameter thermal processes that can be modelled by the cascade of a time constant and a transit delay (ie: boilers without superheaters, furnaces, ovens, vats, torches, fluidised beds, etc) are discussed.
William K. Roots MSc, PhD, WhF, FIEE, Sen Mem IEEE, MIE Aust, Malayappan Shridhar BSc, DMIT, MS (EE)   +1 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Thermal Stability of Pesticides

, 2001
The thermal decomposition of different organophosphorus pesticides has been studied by coupling calorimetric and chemical analysis. Thermodinamic and kinetic information have been obtained, thermal decomposition product distribution assessed and reaction mechanisms proposed.
R. ANDREOZZI, CAPRIO, VINCENZO, MAROTTA, RAFFAELE, R. SANCHIRICO   +3 more
openaire   +3 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

The Effect of Thermal Cycling Treatments on the Thermal Stability and Mechanical Properties of a Ti-Based Bulk Metallic Glass Composite

Metals, 2016
The effect of thermal cycling treatments on the thermal stability and mechanical properties of a Ti48Zr20Nb12Cu5Be15 bulk metallic glass composite (BMGC) has been investigated.
Fan Bu, Jun Wang, Liyuan Li, Hongchao Kou, Xiangyi Xue, Jinshan Li   +5 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Aging, Thermal Cycling and Stability Studies for Nanofluids

, 2015
Stability of nanofluids is one of the critical assessments for the efficient systems that the solid content of nanofluid should be stable and well dispersed for longer time.
Toprak, Muhammet,, Nikkam, Nader,, Muhammad, Mamoun,, Saleemi, Mohsin,   +3 more
core  

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Research Advances in Protein Engineering to Enhance the Thermal Stability of Glycosidase [PDF]

Shipin Kexue
Glycosidase is an indispensable enzyme in the sugar industry. It is difficult to maintain the stability of natural glycosidase during long-term high-temperature sugar conversion, limiting its application in industrial production.
WU Xiaoyi, WU Hao, YANG Can, WEN Shiyu, DUAN Yanting, TAN Wenzhi, XIE Yufei, CHENG Yunhui, WEN Li
doaj   +1 more source