Results 51 to 60 of about 6,691,617 (302)
Impact of phosphorylation on thermal stability of proteins
Nature Methods, 2020 Reversible protein phosphorylation regulates virtually every cellular process and is arguably the most well-studied post-translational modification.
Clément M Potel +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
THERMAL STABILITY STUDY OF GREASE FORMULATED FROM INDUSTRIAL WASTE OIL
Platform, a Journal of Engineering, 2020 This is aimed to investigate the effect of additives on thermal stability of grease formulated with waste transformer oil (WTO). One of the key factors of grease functionality is thermal stability.
W. Rahman +3 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Impacts of nanoscale inclusions on fire retardancy thermal stability and mechanical properties of po
Journal of Thermal Engineering, 2017 A number of different nanoscale inclusions including nanoclay, nanotalc, and graphene were incorporated with polyvinyl chloride (PVC), dispersed in N,N-Dimethylacetmide (DMAC) and cast in rectangular aluminum (Al) molds prior to the testing.
A. Ghazinezami +3 more
doaj
Biotechnology & Biotechnological Equipment, 2022 Protein engineering is an effective method to improve the thermal stability of biological macromolecules. Cytidine monophosphate kinase (CMK) is a key enzyme involved in nucleotide metabolism and participates in the production of cytidine triphosphate ...
Jingjing Wang +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thermal Stability of Polymeric Interlayer Materials
Challenging Glass Conference Proceedings, 2010 Starting with a short summary about chemical and physical fundamentals of different interlayer materials, this article gives an overview about the thermal stability of these analyzed materials.
B. Weller, C. Kothe, M. Kothe
doaj +1 more source