Results 51 to 60 of about 1,419,583 (301)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

On the Thermal Stability of Graphone

, 2011
Molecular dynamics simulation is used to study thermally activated migration of hydrogen atoms in graphone, a magnetic semiconductor formed of a graphene monolayer with one side covered with hydrogen so that hydrogen atoms are adsorbed on each other ...
A. I. Podlivaev, A. I. Podlivaev, A. K. Geim, C. Xu, D. C. Elias, D. W. Boukhvalov, E. M. Pearson, J. O. Sofo, J. V. Andersen, J. Zhao, J. Zhou, K. S. Novoselov, L. A. Chernozatonskii, L. A. Openov, L. A. Openov, L. A. Openov, L. A. Openov, L. A. Openov, L. A. Openov, L. A. Openov, M. M. Maslov, M. M. Maslov, M. M. Maslov, M. M. Maslov, S. Lebegue   +24 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

THERMAL STABILITY STUDY OF GREASE FORMULATED FROM INDUSTRIAL WASTE OIL

Platform, a Journal of Engineering, 2020
This is aimed to investigate the effect of additives on thermal stability of grease formulated with waste transformer oil (WTO). One of the key factors of grease functionality is thermal stability.
W. Rahman, Mohd Aizuddin Abdul Aziz, Norasiha Hamid, N.S.A. Japar   +3 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Poly(amidoamine)s synthesis, characterisation and interaction with BSA [PDF]

, 2014
Cationic poly(amidoamine)s (PAAs) were synthesised and characterised by NMR and gel permeation chromatography. Their thermal properties were investigated using thermogravimetric analysis and differential scanning calorimetry.
Akinc, Almeida, Anand, Antonov, Boeris, Boeris, Brostow, Bujacz, Coué, Danusso, Deep, Dey, Dhalluin, Ferruti, Ferruti, Ferruti, Funhoff, Giancola, Gill, Gu, Julie L. N. Dubois, Kalogeras, Karayianni, Kishimura, Lakowicz, Lavignac, Lavignac, Lavignac, Leader, Liu, Luo, Nathalie Lavignac, Piest, Plesner, Prevette, Ranucci, Richardson, Richardson, Romanini, Seyrek, Tanzi, Torchilin, van der Aa, Vlasova, von Harpe, Won   +45 more
core   +1 more source

High-performance thermal emitters based on laser engineered metal surfaces [PDF]

, 2020
Effective thermal management is of paramount importance for all high-temperature systems operating under vacuum. Cooling of such systems relies mainly on radiative heat transfer requiring high spectral emissivity of surfaces, which is strongly affected ...
Abdolvand, Amin, Barnes, Michael J., Cid, Lorena V., Neupert, Holger, Perez Fontenla, Ana Teresa, Teissandier, Benoit, Wackerow, Stefan, Zolotovskaya, Svetlana A.   +7 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Environmental Stability Design of the Aerial Mapping Camera Based on Multi-Dimensional Compound Structure

Sensors, 2023
Environmental stability technology plays an important role in improving the adaptive range, image resolution and ensuring the stability of geometric parameters of aerial mapping camera.
Hong Yang, Guoqin Yuan, Jie Pan, DeYun Zhou   +3 more
doaj   +1 more source

Effects of Growth Temperatures on the Fatty Acid Composition of Isolated Chloroplasts From Two Species Differing in Heat Sensitivity [PDF]

, 1985
Lipid analyses of chloroplasts isolated from wheat (Triticum aestivum L. cv. Arthur) and milo (Sorghum bicolor cv. Funk\u27s hybrid 522) suggest no major heat effect on lipid class distribution.
Gehring, Roy Z., Todd, Glenn W.
core   +2 more sources