Results 31 to 40 of about 20,145 (265)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Influence of Cold Water Inlets and Obstacles on the Energy Efficiency of the Hot Water Production Process in a Hot Water Storage Tank

Energies, 2021
Domestic hot water preparation is one of the main sources of energy consumption in households. One of the most important elements of domestic hot water (DHW) preparation installation is the storage tank. Its design can significantly affect the efficiency
Agnieszka Malec, Tomasz Cholewa, Alicja Siuta-Olcha   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Numerical simulation of thermal stratification phenomenon in stagnant branch pipe of pressurized water reactors

He jishu
BackgroundIn thermal pipelines of nuclear power systems, thermal stratification is a common phenomenon that can cause stress concentration and deformation of pipeline structures, thereby leading to safety hazards.
MA Jingxiang, DONG Shichang, GONG Shengjie   +2 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Outer Core Stratification From the High Latitude Structure of the Geomagnetic Field

Frontiers in Earth Science, 2018
The presence of stable stratification has broad implications for the thermal and compositional state of the outer core, the evolution of Earth's deep interior, and the energetics of the geodynamo.
Peter Olson, Peter Olson, Maylis Landeau, Maylis Landeau, Evan Reynolds, Evan Reynolds   +5 more
doaj   +1 more source

Characterization of a Recyclate‐Based MgO‐Steel Composite As‐Sintered Inert Anode Candidate After Exposure to Cryolite Electrolysis

Advanced Engineering Materials, EarlyView.
Carbon‐free inert anodes are essential for decarbonizing aluminum electrolysis. This study investigates a recyclate‐based MgO‐316L steel composite anode tested under galvanostatic Hall–Héroult conditions in cryolite at 1000°C. Microstructural analysis reveals selective MgO fluorination, spinel and oxide layer formation, electrolyte infiltration, and ...
Serhii Yaroshevskyi, Alexander Adamczyk, Nora Brachhold, Gert Schmidt, Jana Hubálková, R. Gumeniuk, Alexandros Charitos, Christos G. Aneziris   +7 more
wiley   +1 more source

Thermal and Mass Stratification Effects on MHD Flow Past an Accelerated Vertical Plate with Variable Temperature and Exponential Mass Diffusion Embedded in a Porous Medium

East European Journal of Physics
This study looks at how the impacts of thermal and mass stratification on magnetohydrodynamic (MHD) flow alongside a vertically accelerating plate featuring variable temperature and exponential mass diffusion within a porous medium. The Laplace transform
Digbash Sahu, Rudra Kanta Deka
doaj   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Advanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu, Graca Ferreira Vaz Pinto Mendes, Wanqiao J. Tu, Heping Ma, Toby J. Proctor, Colin R. Butler, Thomas Kjærgaard, Mark W. Lowdell, Martin A. Birchall, Robert E. Hynds, Richard Hewitt, Wenhui Song   +14 more
wiley   +1 more source

PEDOT‐Based Eutectogel Electrode Arrays for Enhanced High‐Resolution Electrogastrography: Fabrication, Stability, and Wearable Performance

Advanced Functional Materials, EarlyView.
Here, we present a high‐density PEDOT eutectogel electrode array for enhanced body surface gastric mapping. Silver electrodes are blade‐coated onto flexible substrates, followed by electrogelation of PEDOT:PSS and the deposition of a PEDOT:LS eutectogel.
Christopher Slaughter, Luke Gatecliff, Xudong Tao, Ruben Ruiz‐Mateos Serrano, Amy T. Jin, Matias L. Picchio, Daniele Mantione, Antonio Dominguez‐Alfaro, George G. Malliaras   +8 more
wiley   +1 more source