Results 41 to 50 of about 375,255 (310)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Investigation of thermal techniques to mitigate buckling distortion in welding panels [PDF]
, 2012 This thesis describes the advancements of the application of thermal tensioning techniques to different weld geometries in order to eliminate buckling distortion.
Nagy, T.
core
Effects of Thermal Stress on Dual Task Performance and Attention Allocation
, 2005 A visual-visual dual task was designed to test the effect of the thermal environment on dual task performance and attention allocation. The temperatures selected for testing were 20 and 35°C Wet Bulb Globe Temperature (WBGT) in experiment 1 and 25, 30 ...
Waldemar Karwowski +7 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Heat Balance When Climbing Mount Everest
Frontiers in Physiology, 2021 Background: Mountaineers must control and regulate their thermal comfort and heat balance to survive the rigors of high altitude environment. High altitudes feature low air pressure and temperatures, strong winds and intense solar radiation, key factors ...
Robert K. Szymczak +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
In-Situ Observation of Propagating-Crack Front Geometry in Thermal Stress Cleaving of Thin Glass Plates [PDF]
, 2009 Geometry of propagating crack front and crack opening displacement were observed in situ in thermal stress cleaving of thin soda-lime glass plates using the interference fringe method.
才本, 明秀 +2 more
core
Nihon Kikai Gakkai ronbunshu, 2014 When a porous solid is subjected to both gas infiltration and heat transfer, thermal stresses are generated in such a solid. In the previous reports, fundamental theory for a porous solid under such a complex situation was developed, and then a thermal ...
Masayuki ARAI
doaj +1 more source