Results 51 to 60 of about 1,081,770 (308)

YoeB toxin is activated during thermal stress. [PDF]

open access: yes, 2015
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando   +2 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Rubber friction on smooth surfaces

open access: yes, 2006
We study the sliding friction for viscoelastic solids, e.g., rubber, on hard flat substrate surfaces. We consider first the fluctuating shear stress inside a viscoelastic solid which results from the thermal motion of the atoms or molecules in the solid.
A. I. Volokitin   +23 more
core   +1 more source

Thermally induced mechanical stress in the stator windings of electrical machines [PDF]

open access: yes, 2018
The lifetime of an electrical machine mainly depends on the thermal overloading. Modern day applications of electrical machines on one hand require compact machines with high power density, while on the other hand force electrical machines to undergo ...
Sergeant, Peter, Silwal, Bishal
core   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Air-Holes Collapse Properties of Photonic Crystal Fiber in Heating Process by $\hbox{CO}_{2}$ Laser

open access: yesIEEE Photonics Journal, 2012
For the fusion splicing of photonic crystal fiber (PCF), the air-hole collapse in heating process is important for minimizing the splicing loss. To analyze the air-hole collapse properties in heating process by CO2 laser, a theoretical model of PCF has ...
G. Fu, W. Jin, X. Fu, W. Bi
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Thermal Stresses V [PDF]

open access: yesJournal of Applied Mechanics, 2000
[S0021-8936(00)03202-5]
R. B. Hetnarski,, D. H. Allen,
openaire   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Evolution of interfacial dislocation network during anisothermal high-temperature creep of a nickel-based superalloy [PDF]

open access: yes, 2011
The effect of thermal cycling creep on the dislocation networks at the γ/γ′ interfaces in the MC2 superalloy is investigated. Tensile creep tests were performed under thermal cycling and isothermal conditions at low stress (80 MPa) and high temperature ...
Coujou, Armand   +4 more
core   +4 more sources

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