Results 71 to 80 of about 7,330,827 (405)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Developing specific molecular biomarkers for thermal stress in salmonids

BMC Genomics, 2018
Pacific salmon (Oncorhynchus spp.) serve as good biological indicators of the breadth of climate warming effects on fish because their anadromous life cycle exposes them to environmental challenges in both marine and freshwater environments.
A. Akbarzadeh, O. Günther, A. L. Houde, Shaorong Li, Tobi J. Ming, K. Jeffries, S. Hinch, K. Miller   +7 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The influence of the Curing Residual Thermal Stresses and Post-Stretching Process on Glare Laminate [PDF]

, 2021
Fernando Otero, F. Turón, J. Gois de Freitas, C. van Hengel, H. de Frel, Xavier Martínez   +5 more
openalex   +1 more source

Symbiodinium Functional Diversity in the Coral Siderastrea siderea Is Influenced by Thermal Stress and Reef Environment, but Not Ocean Acidification

Frontiers in Marine Science, 2018
Coral bleaching events are increasing in frequency, demanding examination of the physiological and molecular responses of scleractinian corals and their algal symbionts (Symbiodinium sp.) to stressors associated with bleaching.
S. Davies, J. Ries, A. Marchetti, K. Castillo   +3 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fundamental solution of thermal stress field in porous infinite media subjected to gas infiltration and heat transfer

Nihon Kikai Gakkai ronbunshu, 2014
When a porous solid is subjected to both gas infiltration and heat transfer, thermal stresses are generated in such a solid. In the previous reports, fundamental theory for a porous solid under such a complex situation was developed, and then a thermal ...
Masayuki ARAI
doaj   +1 more source

Heat Balance When Climbing Mount Everest

Frontiers in Physiology, 2021
Background: Mountaineers must control and regulate their thermal comfort and heat balance to survive the rigors of high altitude environment. High altitudes feature low air pressure and temperatures, strong winds and intense solar radiation, key factors ...
Robert K. Szymczak, Krzysztof Błażejczyk   +1 more
doaj   +1 more source

Rubber friction on smooth surfaces

, 2006
We study the sliding friction for viscoelastic solids, e.g., rubber, on hard flat substrate surfaces. We consider first the fluctuating shear stress inside a viscoelastic solid which results from the thermal motion of the atoms or molecules in the solid.
A. I. Volokitin, B. N. J. Persson, Baumberger, Casoli, Chernyak, Filippov, Gal, Grosch, Klüppel, Persson, Persson, Persson, Persson, Persson, Persson, Persson, Persson, Roberts, Schallamach, Schallamach, Tartaglino, vibrations, Vorvolakos, Williams   +23 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source