Results 111 to 120 of about 15,587 (201)

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Thermodynamic description of Eu(NO₃)₃-NaNO₃-H₂O and Eu(NO₃)₃-Mg(NO₃)₂-H₂O systems. Solubility experiments and full dissociation Pitzer models. [PDF]

RSC Adv
Häusler F, F Dos Santos P, Lassin A, Gaona X, Garbev K, Touzelet S, Cartigny Y, Altmaier M, Madé B.   +8 more
europepmc   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

Advanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo, Yu He, Shuyao Li, Haoyu Guan, Ruili Cui, Yu Shi, Zhongwen Jiang, Siyu Wang, Xuan Li, Jiyuan Li, Mei Hu, Yupeng Zhou, Beisha Tang, Yanyan Zhang, Zhaobing Gao, Yu Zhou, Zhenhua Liu, Ping Li   +17 more
wiley   +1 more source

Thermodynamic Insights Into Direct Methane to Methanol Conversion Using O₂ and CO₂ Oxidants. [PDF]

ChemistryOpen
Sumikawa VIO, Bueno JMC, Dantas SC, Lima AM.   +3 more
europepmc   +1 more source

Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics

Advanced Science, EarlyView.
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley   +1 more source

From Quantum Mechanics to Coarse-Grained Models: Bridging the Gap toward Polymer Rational Design. [PDF]

J Chem Theory Comput
Semmeq A, Ugartemendia A, Mossa A, Coiai S, Brancolini G, Prampolini G.   +5 more
europepmc   +1 more source

Green and Low‐Carbon Synthesis of Lithium Sulfide (Li2S): From Fundamental Mechanisms to Scalable Manufacturing for Next‐Generation Energy Storage

Advanced Science, EarlyView.
This review focuses on green synthesis routes for lithium sulfide (Li2S)—a key material for lithium–sulfur batteries and sulfide solid electrolytes, whose traditional carbothermal reduction remains energy‐intensive and unsustainable. Specifically examined routes include low‐temperature solid‐state reactions, magnesiothermal reduction, and solution ...
Aiping Peng, Xingtao Qi, Lingfeng Zhu, Ningrui Zhan, Yaohui Qu, Hui Li, Hai Zhang, Fan Wang, Ze Zhang, Xuewen Wang, Zhenyu Yang, Tianyi Ma   +11 more
wiley   +1 more source

ThermoPred: AI-Enhanced Quantum Chemistry Data Set and ML Toolkit for Thermochemical Properties of API-Like Compounds and Their Degradants. [PDF]

J Chem Inf Model
Santos DP, Dias-Silva JR, Júnior LHKQ, de Oliveira HCB.   +3 more
europepmc   +1 more source

Data‐Driven Discovery of Unconventional Antiferromagnets

Advanced Science, EarlyView.
A high‐throughput workflow that combines the physics‐informed pre‐screening, high‐throughput exchange calculations, Luttinger‐Tisza analysis and symmetry classification is established for accurate identification of unconventional antiferromagnets from the broad structural database.
Qirui Cui, Chenxu Liu, Anna Delin, Kaiyou Wang   +3 more
wiley   +1 more source