Results 131 to 140 of about 39,448 (266)

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

open access: yesPhotochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin   +8 more
wiley   +1 more source

Transcriptional benchmark dose modeling of ultraviolet radiation‐induced genomic activation in mouse skin

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to ultraviolet radiation (UV‐R) from tanning equipment increases skin cancer risk through molecular changes, but genomic thresholds remain unclear. Using mice, we examined dose‐ and time‐dependent gene expression after erythemally‐weighted UV‐R doses (0–40 mJ/cm2).
Sami S. Qutob   +10 more
wiley   +1 more source

The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long‐duration spaceflight

open access: yesExperimental Physiology, EarlyView.
Abstract The current understanding of crew health maintenance is founded upon decades of physiological research conducted in terrestrial spaceflight analogues and in low Earth orbit, particularly on the International Space Station. However, as we progress towards the Lunar Gateway and interplanetary missions, it is imperative that the tools employed to
Rodrigo Fernandez‐Gonzalo   +3 more
wiley   +1 more source

How hot is too hot for people? A review of empirical models of perceptual, physiological and functional limits of human heat tolerance

open access: yesExperimental Physiology, EarlyView.
Abstract How hot is too hot for people? This is a question that human thermal physiologists are asked often by a variety of knowledge users across the public and private sectors, who have grown aware of the negative impact of global warming on people's health and quality of life.
Davide Filingeri, Nuno Koch Esteves
wiley   +1 more source

Topical application of the cold‐mimetic l‐menthol decreases wheel running without affecting the beneficial effects of voluntary exercise in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Topical application of l‐menthol, a pharmacological cold‐mimetic and agonist of the cold‐sensing receptor TRPM8 (transient receptor potential cation channel subfamily M member 8), has been shown to stimulate brown adipose tissue (BAT) thermogenesis and reduce weight gain in both obese and lean male mice, without affecting energy intake.
Annalaura Bellucci   +8 more
wiley   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

open access: yesExperimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su   +4 more
wiley   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid   +13 more
wiley   +1 more source

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