Results 91 to 100 of about 9,144 (206)

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng, Huan Li, Jun Wang, Li‐Chao Wang, Hui‐Zi Liu, Xiao‐Feng Dai, Steven J. Klosterman, Jie‐Yin Chen, Krishna V. Subbarao, Feng‐Mao Chen, Dan‐Dan Zhang   +10 more
wiley   +1 more source

Plasmon‐Induced Optothermal Manipulation of Colloidal Particles and Biological Entities Resilient to Saline Environments

Advanced Optical Materials, Volume 14, Issue 29, 7 August 2026.
The particle with high surface hydrophilicity exhibits strong thermophoretic attraction, as its dense hydration layer enhances the role of interfacial water molecules in determining thermophoretic mobility over other ionic effects. This finding elucidates the mechanism underlying the robust thermophoretic accumulation of Escherichia coli in high ...
Seungyeop Kang, Louis Quaire‐‐Merlin, Alex J. Thompson, Jang Ah Kim   +3 more
wiley   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng, Haiyan Zhou, Wang Xia, Hongxiang Wu, Xuechen Li   +4 more
wiley   +2 more sources

Influence of Heat and Mass Transmission on the MHD Fluid Circulation in Conjunction with an Upright Surface in the Emergence of Radiation Thermophoresis and the Dufour Repercussions

East European Journal of Physics
The current research simulates the mass and heat energy transmission model on MHD fluid flow under concentration and temperature deviations on a two-dimensional viscous fluid along an upright facet.
Ashik Hussain Mirza, Bamdeb Dey, Rita Choudhury   +2 more
doaj   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, Volume 2, Issue 4, August 2026.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Physapubescin B From Physalis: A Food‐Derived Withanolide for Cancer Chemoprevention and Nutraceutical Development

eFood, Volume 7, Issue 4, August 2026.
Physapubescin B may interfere with multiple cancer‐associated signaling pathways by inhibiting Ras/Raf/mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase (Ras/Raf/MEK/ERK) signaling and vascular endothelial growth factor (VEGF)‐dependent angiogenesis.
Wojciech Koch, Katarzyna Stępnik, Anna Wawruszak, Estera Okoń, Agata Jarząb, Katarzyna Gaweł‐Bęben, Magdalena Michalak‐Tomczyk, Jacek Jachuła, Magdalena Zdziebło, Paweł Helon, Javad Sharifi‐Rad, Daniela Calina   +11 more
wiley   +1 more source

Modeling and Analysis of Nonlinear Radiative and Electromagnetic Effects With Second‐Order Slip in Unsteady Hybrid Nanofluid Flow Past a Porous Stretching Surface

Engineering Reports, Volume 8, Issue 8, August 2026.
The current work examines the dynamics of the stagnation point flow of an unsteady hybrid nanofluid (Fe2O3–Cu/H2O) across an inclined porous stretching surface. It considers heat transfer, second‐order slip, electrical field, heat source/sink, mixed convection, and magnetic field effects, as well as linear and nonlinear radiation.
Mazhar Hussain, Sadia Hameed, Muhammad Zohaib Hanif, Mubashir Qayyum, Saraswati Acharya   +4 more
wiley   +1 more source

A numerical analysis of heat and mass transfer in water-based hybrid nanofluid flow containing copper and alumina nanoparticles over an extending sheet

Nanotechnology Reviews
This article investigates two-dimensional micropolar flow over an expanding sheet of water-based hybrid nanofluid comprising copper and alumina nanoparticles with the impact of the magnetic field.
Yasmin Humaira, Bossly Rawan, Alduais Fuad S., Al-Bossly Afrah, Saeed Anwar   +4 more
doaj   +1 more source

Computational Investigation of MHD Radiative Flow of Shape‐Dependent Al2O3$$ A{l}_2{O}_3 $$ and Fe3O4$$ F{e}_3{O}_4 $$ Nanofluids in A Semi‐Porous Channel

Engineering Reports, Volume 8, Issue 8, August 2026.
A computational study of unsteady MHD radiative nanofluid flow in a semi‐porous channel reveals that nanoparticle shape, volume fraction, and magnetic effects significantly influence velocity and heat transfer. Results highlight strong coupling between geometric, electromagnetic, and thermophysical parameters in optimizing thermal system performance ...
Mahmmoud M. Syam, Sondos M. Syam, Muhammed I. Syam   +2 more
wiley   +1 more source

The Pharmacology of the SLC15A4‐TASL Complex, an Emerging Target for the Treatment of Lupus

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT SLC15A4 is a member of the solute carrier superfamily that has been strongly linked to the pathogenesis of the auto‐immune disease SLE. The endo‐lysosomally localized SLC15A4 has traditionally been considered a proton‐dependent histidine and peptide transporter, but has also been shown to facilitate TLR7, 8, and 9 induced IFN‐alpha signaling ...
Alex L. Wilkinson, Dillon Popat, Kathy Sengmany, Miguel C. Silva, Steven J. Charlton, Charles S. Lay   +5 more
wiley   +1 more source