Results 41 to 50 of about 1,676 (198)

Thermosensation and longevity [PDF]

open access: yesJournal of Comparative Physiology A, 2015
Temperature has profound effects on behavior and aging in both poikilotherms and homeotherms. To thrive under the ever fluctuating environmental temperatures, animals have evolved sophisticated mechanisms to sense and adapt to temperature changes. Animals sense temperature through various molecular thermosensors, such as thermosensitive transient ...
Rui, Xiao, Jianfeng, Liu, X Z Shawn, Xu
openaire   +2 more sources

TRP channels in thermosensation

open access: yesCurrent Opinion in Neurobiology, 2022
The ability to sense external temperature is assumed by somatosensory neurons, in which temperature information is converted to neural activity by afferent input to the central nervous system. Somatosensory neurons consist of various populations with specialized gene expression, including thermosensitive transient receptor potential ion channels ...
Makiko Kashio, Makoto Tominaga
openaire   +2 more sources

The physiological role of TRP channels in sleep and circadian rhythm. [PDF]

open access: yesJ Cell Mol Med
Abstract TRP channels, are non‐specific cationic channels that are involved in multiple physiological processes that include salivation, cellular secretions, memory extinction and consolidation, temperature, pain, store‐operated calcium entry, thermosensation and functionality of the nervous system.
Woodard GE, Rosado JA, Li H.
europepmc   +2 more sources

Genome-Wide Identification of Transcription Start Sites Yields a Novel Thermosensing RNA and New Cyclic AMP Receptor Protein-Regulated Genes in Escherichia coli

open access: yesJournal of Bacteriology, 2011
Intergenic regions often contain regulatory elements that control the expression of flanking genes. Using a deep-sequencing approach, we identified numerous new transcription start sites in Escherichia coli, yielding a new thermosensing regulatory RNA ...
Rahul Raghavan, A. Sage, H. Ochman
semanticscholar   +2 more sources

Cells and circuits for thermosensation in mammals [PDF]

open access: yesNeuroscience Letters, 2019
How is temperature detected and how is the resulting sensory information synthesized to produce appropriate thermosensory responses? Research in the last few years has gone a long way to answering the first part of this question. Excitingly, recent research has uncovered some of the ways sensory inputs are processed spinally, as well as identifying ...
Hans Jürgen, Solinski, Mark A, Hoon
openaire   +2 more sources

The role of TRPA1 channels in thermosensation

open access: yesCell Insight, 2022
Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel sensitive to different physical and chemical stimuli. TRPA1 is associated with many important physiological functions in different species and thus is involved in different degrees of evolution.
Hao Zhang   +6 more
openaire   +3 more sources

Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin

open access: yeseLife, 2016
Venom toxins are invaluable tools for exploring the structure and mechanisms of ion channels. Here, we solve the structure of double-knot toxin (DkTx), a tarantula toxin that activates the heat-activated TRPV1 channel. We also provide improved structures
Chanhyung Bae   +10 more
doaj   +1 more source

What Temperature of Coffee Exceeds the Pain Threshold? Pilot Study of a Sensory Analysis Method as Basis for Cancer Risk Assessment

open access: yesFoods, 2018
The International Agency for Research on Cancer (IARC) evaluates “very hot (>65 °C) beverages” as probably carcinogenic to humans. However, there is a lack of research regarding what temperatures consumers actually perceive as &ldquo ...
Julia Dirler   +2 more
doaj   +1 more source

Photophysical Investigation of a Benzimidazole Derivative and Its Applications in Selective Detection of Fe3+, Thermosensing and Logic Gates

open access: yesJournal of Fluorescence, 2021
The fluorescence based applications such as chemosensing of Fe3+ ion, temperature sensing, NOR-gate molecular logic operations, and fluorescent ink were achieved using an expired medicine namely Pantoprazole (sensor1) which is a derivative of ...
A. Nadgir, Ashok H. Sidarai
semanticscholar   +1 more source

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