Results 51 to 60 of about 1,676 (198)
Engineering vanilloid-sensitivity into the rat TRPV2 channel
eLife, 2016 The TRPV1 channel is a detector of noxious stimuli, including heat, acidosis, vanilloid compounds and lipids. The gating mechanisms of the related TRPV2 channel are poorly understood because selective high affinity ligands are not available, and the ...
Feng Zhang +8 more
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RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion.
PLoS Pathogens, 2021 Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae and Haemophilus influenzae, are the major causative agents of bacterial meningitis, attributing to ...
Hannes Eichner +6 more
doaj +1 more source
Crystals, 2021 Photoluminescent liquid crystals (PLLCs) have attracted significant attention owing to their broad applicability in thermosensing and PL switching.
Shigeyuki Yamada +10 more
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Accurate prediction of thermoresponsive phase behavior of disordered proteins. [PDF]
Protein SciAbstract Under heat stress, proteins have been shown to organize into biomolecular condensates in living cells. Recent experiments suggest that this response may be encoded in the chemical makeup of proteins. In particular, specific sequences undergo phase separation at elevated temperatures, exhibiting lower critical solution temperatures (LCST ...
Chakravarti A, Joseph JA.
europepmc +2 more sources
Injury Threshold of Oral Contact with Hot Foods and Method for Its Sensory Evaluation
Safety, 2018 Epidemiological studies indicate an increased risk of esophageal cancer from the consumption of very hot foods and beverages. The contact time and the contact temperature are decisive for the risk of injury.
Dirk W. Lachenmeier, Walter Lachenmeier
doaj +1 more source
mBio, 2019 Environmental awareness is an essential attribute of all organisms. The homeoviscous adaptation system of Bacillus subtilis provides a powerful experimental model for the investigation of stimulus detection and signaling mechanisms at the molecular level.
Pilar Fernández +6 more
doaj +1 more source
TREKing noxious thermosensation [PDF]
The EMBO Journal, 2009 The ability to sense environmental temperature as pleasant or unpleasant is associated with the activity of thermo‐sensitive neurons in the peripheral nervous system. Differential sensation of pleasant environmental temperatures (warm and cool) versus unpleasant and noxious (cold and hot) temperatures requires the definition of thresholds and ...
openaire +2 more sources
The Cellular Code for Mammalian Thermosensation [PDF]
The Journal of Neuroscience, 2013 Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably discriminate hot from cold and to select their preferred environments. Previously, we generated mice that are completely insensitive to temperatures from noxious cold to painful heat (−5 to 55°C) by ablating several different classes of nociceptor early in ...
Leah A, Pogorzala +2 more
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Temperature Sensing in Plants: On the Dawn of Molecular Thermosensor Research [PDF]
, 2022 text学術雑誌論文 / Journal ArticleAlthough many studies on plant growth and development focus on the effects of light, a growing number of studies dissect plant responses to temperature and the underlying signaling pathways. The identity of plant thermosensing
Kodama, Yutaka, Noguchi, Minoru
core +1 more source
A Systematic Review of Thermosensation and Thermoregulation in Anxiety Disorders [PDF]
Frontiers in Physiology, 2021 Graphical AbstractThis systematic review sought to summarise studies comparing thermosensory and thermoregulatory functioning between individuals with anxiety disorders and healthy controls. Its main findings are summarised on the right side.
Fischer, Susanne +2 more
openaire +4 more sources